ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ribosomal protein S6 kinase, 90kDa, polypeptide 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000072133 RPS6KA6 9606 - X:84058346-84187925 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262752 RPS6KA6-001 84063976-84187907 protein_coding
  ENST00000460730 RPS6KA6-002 84156075-84187898 processed_transcript
  ENST00000495332 RPS6KA6-003 84096194-84106461 processed_transcript
  ENST00000543399 RPS6KA6-201 84064248-84187925 protein_coding
  ENST00000620340 RPS6KA6-202 84058346-84186141 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000262752ENST00000495332ENST00000543399ENST00000620340
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000262752 N/A 0.155±0.11 0.106±0.00 0.141±0.10
ENST00000495332 N/A 0.249±0.22 0.515±0.00 N/A
ENST00000543399 0.048±0.00 0.067±0.06 N/A 0.069±0.03
ENST00000620340 N/A 0.058±0.05 0.079±0.00 0.059±0.03

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003KW CIL_0003KW_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0006978 IMP DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0007165 TAS signal transduction
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0007417 TAS central nervous system development
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0035556 IEA intracellular signal transduction
GO:0045992 ISS negative regulation of embryonic development
GO:0070373 ISS negative regulation of ERK1 and ERK2 cascade
GO:2000381 ISS negative regulation of mesoderm development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000025665 Rps6ka6 protein_coding Mus_musculus

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