ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: ribosomal protein S6 kinase, 90kDa, polypeptide 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000543399 RPS6KA6-201 ENSG00000072133 9606 - X:84064248-84187925 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHUVECENST00000543399
Transcript ID BECs HAoEC HUVEC
ENST00000543399 0.048±0.00 0.067±0.06 0.069±0.03

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0006978 IMP DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0007165 TAS signal transduction
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0007417 TAS central nervous system development
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0035556 IEA intracellular signal transduction
GO:0045992 ISS negative regulation of embryonic development
GO:0070373 ISS negative regulation of ERK1 and ERK2 cascade
GO:2000381 ISS negative regulation of mesoderm development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000082034 Rps6ka6-201 protein_coding Mus_musculus 0 2566
ENSMUST00000096348 Rps6ka6-001 protein_coding Mus_musculus 0 2566
ENSMUST00000137712 Rps6ka6-003 protein_coding Mus_musculus 0 2560
ENSMUST00000113428 Rps6ka6-011 protein_coding Mus_musculus 0 2486
ENSMUST00000065976 Rps6ka6-002 protein_coding Mus_musculus 0 2440
ENSMUST00000138645 Rps6ka6-010 protein_coding Mus_musculus 0 414
ENSMUST00000123213 Rps6ka6-004 protein_coding Mus_musculus 0 374
ENSMUST00000128819 Rps6ka6-005 protein_coding Mus_musculus 0 195
ENSMUST00000123102 Rps6ka6-009 nonsense_mediated_decay Mus_musculus 2e-33 148
ENSMUST00000132319 Rps6ka6-007 protein_coding Mus_musculus 0.0000000000008 81
ENSMUST00000123951 Rps6ka6-008 protein_coding Mus_musculus 0.00000000003 75

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