ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: Rho guanine nucleotide exchange factor (GEF) 10-like
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000074964 ARHGEF10L 9606 + 1:17539835-17697874 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000167825 ARHGEF10L-005 17626007-17697868 nonsense_mediated_decay
  ENST00000361221 ARHGEF10L-001 17539835-17697869 protein_coding
  ENST00000375408 ARHGEF10L-002 17618316-17697868 protein_coding
  ENST00000375415 ARHGEF10L-003 17580553-17697649 protein_coding
  ENST00000466782 ARHGEF10L-009 17639753-17654665 processed_transcript
  ENST00000469726 ARHGEF10L-004 17615088-17697860 processed_transcript
  ENST00000482359 ARHGEF10L-008 17634257-17638003 processed_transcript
  ENST00000482892 ARHGEF10L-007 17602171-17604882 processed_transcript
  ENST00000495593 ARHGEF10L-006 17694047-17697874 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000167825ENST00000361221ENST00000375408ENST00000375415ENST00000469726ENST00000495593
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000167825 N/A 0.048±0.01 0.589±0.00 0.046±0.00 N/A
ENST00000361221 N/A N/A N/A N/A 0.315±0.35
ENST00000375408 0.235±0.00 0.180±0.00 N/A N/A 0.239±0.05
ENST00000375415 N/A 0.222±0.08 N/A N/A 0.486±0.30
ENST00000469726 N/A N/A N/A N/A 0.081±0.04
ENST00000495593 N/A N/A N/A N/A 0.141±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000236 CIL_000236_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074244 arhgef10lb protein_coding Danio_rerio
ENSDARG00000088630 arhgef10la protein_coding Danio_rerio
ENSMUSG00000040964 Arhgef10l protein_coding Mus_musculus

Loading