ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: solute carrier family 46 (folate transporter), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000076351 SLC46A1 9606 - 17:28394756-28407197 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000578217 SLC46A1-007 28404240-28405747 processed_transcript
  ENST00000581516 SLC46A1-005 28405377-28407197 protein_coding
  ENST00000582590 SLC46A1-004 28404316-28406168 retained_intron
  ENST00000582735 SLC46A1-008 28399346-28404821 protein_coding
  ENST00000584426 SLC46A1-011 28405048-28406599 protein_coding
  ENST00000584995 SLC46A1-006 28404724-28406630 protein_coding
  ENST00000612814 SLC46A1-001 28394756-28406210 protein_coding
  ENST00000618626 SLC46A1-002 28395676-28406201 protein_coding
  ENST00000619923 SLC46A1-012 28400518-28401045 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000612814ENST00000618626
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000612814 1.573±0.70 N/A 1.574±0.92
ENST00000618626 3.729±1.34 0.601±0.00 2.294±1.07

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000FM CIL_0000FM_0002 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005542 IEA folic acid binding
GO:0005737 ISS cytoplasm
GO:0005886 TAS plasma membrane
GO:0006766 TAS vitamin metabolic process
GO:0006767 TAS water-soluble vitamin metabolic process
GO:0006879 TAS cellular iron ion homeostasis
GO:0008517 IDA folic acid transporter activity
GO:0009986 IDA cell surface
GO:0015232 IEA heme transporter activity
GO:0015350 IEA methotrexate transporter activity
GO:0015884 IDA folic acid transport
GO:0015886 IEA heme transport
GO:0016021 IEA integral component of membrane
GO:0016324 IDA apical plasma membrane
GO:0022857 IEA transmembrane transporter activity
GO:0031526 IEA brush border membrane
GO:0044281 TAS small molecule metabolic process
GO:0046655 TAS folic acid metabolic process
GO:0051958 IEA methotrexate transport
GO:0055085 IEA transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026149 slc46a1 protein_coding Danio_rerio
ENSMUSG00000020829 Slc46a1 protein_coding Mus_musculus

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