ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: guanine nucleotide binding protein (G protein), beta polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000078369 GNB1 9606 - 1:1785285-1891117 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000378609 GNB1-001 1785286-1891056 protein_coding
  ENST00000434686 GNB1-007 1793245-1890401 protein_coding
  ENST00000437146 GNB1-006 1804526-1832285 protein_coding
  ENST00000439272 GNB1-005 1790565-1890836 protein_coding
  ENST00000461893 GNB1-003 1787987-1794197 retained_intron
  ENST00000471354 GNB1-002 1789061-1818386 retained_intron
  ENST00000472614 GNB1-008 1824988-1890966 processed_transcript
  ENST00000607589 GNB1-009 1824988-1825554 retained_intron
  ENST00000610897 GNB1-201 1785285-1891117 protein_coding
  ENST00000615252 GNB1-202 1785285-1891117 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000378609ENST00000461893ENST00000610897ENST00000615252
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000378609 28.274±0.00 36.773±23.05 77.097±0.00 53.851±54.38
ENST00000461893 N/A N/A N/A 7.422±5.21
ENST00000610897 N/A 12.387±0.00 N/A 17.382±7.30
ENST00000615252 21.046±0.00 N/A N/A N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001664 IEA G-protein coupled receptor binding
GO:0001750 IEA photoreceptor outer segment
GO:0001917 IEA photoreceptor inner segment
GO:0003924 IDA GTPase activity
GO:0004871 IEA signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005622 ISS intracellular
GO:0005765 IDA lysosomal membrane
GO:0005834 IDA heterotrimeric G-protein complex
GO:0005886 TAS plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0006184 IDA GTP catabolic process
GO:0007165 TAS signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007191 ISS adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007200 IEA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007213 TAS G-protein coupled acetylcholine receptor signaling pathway
GO:0007265 TAS Ras protein signal transduction
GO:0007268 TAS synaptic transmission
GO:0007596 TAS blood coagulation
GO:0007603 TAS phototransduction, visible light
GO:0008283 IEA cell proliferation
GO:0010659 IEA cardiac muscle cell apoptotic process
GO:0016020 ISS membrane
GO:0016056 TAS rhodopsin mediated signaling pathway
GO:0022400 TAS regulation of rhodopsin mediated signaling pathway
GO:0030168 TAS platelet activation
GO:0030425 IEA dendrite
GO:0030507 IEA spectrin binding
GO:0031702 IEA type 1 angiotensin receptor binding
GO:0031982 IDA vesicle
GO:0032403 IDA protein complex binding
GO:0042622 IEA photoreceptor outer segment membrane
GO:0044281 TAS small molecule metabolic process
GO:0044297 IEA cell body
GO:0050909 IEA sensory perception of taste
GO:0051020 IPI GTPase binding
GO:0060041 IEA retina development in camera-type eye
GO:0070062 IDA extracellular vesicular exosome
GO:0071377 TAS cellular response to glucagon stimulus
GO:0071380 ISS cellular response to prostaglandin E stimulus
GO:0071456 IEA cellular response to hypoxia
GO:0071870 ISS cellular response to catecholamine stimulus
GO:0097381 TAS photoreceptor disc membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090454 gnb1a protein_coding Danio_rerio
ENSMUSG00000029064 Gnb1 protein_coding Mus_musculus

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