ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: SUMO1/sentrin specific peptidase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000079387 SENP1 9606 - 12:48042898-48106308 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000448372 SENP1-002 48042974-48105808 protein_coding
  ENST00000547181 SENP1-007 48088553-48106046 retained_intron
  ENST00000547886 SENP1-009 48080084-48096427 processed_transcript
  ENST00000549518 SENP1-004 48045322-48106308 protein_coding
  ENST00000549595 SENP1-003 48045322-48101472 protein_coding
  ENST00000549882 SENP1-005 48097737-48106066 retained_intron
  ENST00000551358 SENP1-008 48063631-48065680 retained_intron
  ENST00000551592 SENP1-010 48080093-48098034 processed_transcript
  ENST00000551798 SENP1-006 48083695-48106052 protein_coding
  ENST00000552189 SENP1-001 48042898-48105834 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000448372ENST00000549518ENST00000549595ENST00000552189
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000448372 4.278±1.84 4.877±0.00 3.997±0.92
ENST00000549518 4.699±0.00 N/A N/A
ENST00000549595 N/A N/A 2.346±0.00
ENST00000552189 N/A N/A 2.556±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00079B CIL_00079B_0001 CGP
CIL_00068J CIL_00068J_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004175 TAS endopeptidase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005925 IDA focal adhesion
GO:0006508 IEA proteolysis
GO:0006919 IMP activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0008234 IEA cysteine-type peptidase activity
GO:0010724 IEA regulation of definitive erythrocyte differentiation
GO:0016925 TAS protein sumoylation
GO:0016926 IMP protein desumoylation
GO:0016929 ISS SUMO-specific protease activity
GO:0031965 IDA nuclear membrane
GO:0032435 IEA negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0097190 IMP apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078574 SENP1 protein_coding Danio_rerio
ENSMUSG00000033075 Senp1 protein_coding Mus_musculus

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