ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: regulatory factor X, 3 (influences HLA class II expression)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000080298 RFX3 9606 - 9:3218297-3526004 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302303 RFX3-201 3270930-3489487 protein_coding
  ENST00000358730 RFX3-005 3247037-3395596 protein_coding
  ENST00000381984 RFX3-001 3344732-3395588 protein_coding
  ENST00000382004 RFX3-006 3218297-3525983 protein_coding
  ENST00000420720 RFX3-010 3323961-3346764 protein_coding
  ENST00000442560 RFX3-009 3323961-3346764 protein_coding
  ENST00000449190 RFX3-004 3330317-3526004 protein_coding
  ENST00000449234 RFX3-007 3247514-3257199 protein_coding
  ENST00000451859 RFX3-002 3301543-3489428 protein_coding
  ENST00000457373 RFX3-003 3293084-3489416 protein_coding
  ENST00000458034 RFX3-008 3257002-3270738 protein_coding
  ENST00000617270 RFX3-202 3218302-3526001 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000302303ENST00000358730ENST00000382004ENST00000449190ENST00000457373ENST00000617270
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000302303 N/A 0.541±0.00 N/A N/A N/A
ENST00000358730 N/A 0.292±0.00 0.950±0.00 N/A 0.582±0.00
ENST00000382004 N/A 0.292±0.00 N/A N/A 0.508±0.02
ENST00000449190 N/A N/A N/A N/A 6.541±3.50
ENST00000457373 N/A N/A N/A N/A 2.160±0.00
ENST00000617270 0.094±0.00 0.620±0.42 N/A 1.104±0.00 1.289±0.81

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000NH CIL_0000NH_0001 CGP
CIL_0009AI CIL_0009AI_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0003677 IEA:TAS DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0003705 TAS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA:IC nucleus
GO:0005667 IC transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0006355 ISS:IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0007368 IEA determination of left/right symmetry
GO:0031018 ISS endocrine pancreas development
GO:0042384 ISS cilium assembly
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0048469 ISS cell maturation
GO:0050796 ISS regulation of insulin secretion
GO:0060285 ISS cilium-dependent cell motility
GO:0060287 ISS epithelial cilium movement involved in determination of left/right asymmetry
GO:0072560 IEA type B pancreatic cell maturation
GO:2000078 ISS positive regulation of type B pancreatic cell development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014550 rfx3 protein_coding Danio_rerio
ENSMUSG00000040929 Rfx3 protein_coding Mus_musculus

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