ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: regulatory factor X, 3 (influences HLA class II expression)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000617270 RFX3-202 ENSG00000080298 9606 - 9:3218302-3526001 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000617270
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000617270 0.094±0.00 0.620±0.42 1.104±0.00 1.289±0.81

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0003677 IEA:TAS DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0003705 TAS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA:IC nucleus
GO:0005667 IC transcription factor complex
GO:0006355 ISS:IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0031018 ISS endocrine pancreas development
GO:0042384 ISS cilium assembly
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0048469 ISS cell maturation
GO:0050796 ISS regulation of insulin secretion
GO:0060285 ISS cilium-dependent cell motility
GO:0060287 ISS epithelial cilium movement involved in determination of left/right asymmetry
GO:2000078 ISS positive regulation of type B pancreatic cell development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000165566 Rfx3-201 protein_coding Mus_musculus 0 5256
ENSMUST00000046898 Rfx3-003 protein_coding Mus_musculus 0 4447
ENSMUST00000174850 Rfx3-001 protein_coding Mus_musculus 0 3860
ENSMUST00000172907 Rfx3-004 protein_coding Mus_musculus 0 3373
ENSMUST00000172498 Rfx3-006 processed_transcript Mus_musculus 0 2758
ENSMUST00000173863 Rfx3-005 nonsense_mediated_decay Mus_musculus 0 1190
ENSMUST00000173161 Rfx3-002 retained_intron Mus_musculus 0 957
ENSDART00000041236 rfx3-201 protein_coding Danio_rerio 0.000000000000005 90
ENSDART00000144882 rfx3-001 protein_coding Danio_rerio 0.000000000000005 90

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