ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: GNAS complex locus
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000087460 GNAS 9606 + 20:58839718-58911192 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265620 GNAS-035 58891364-58911192 protein_coding
  ENST00000306090 GNAS-201 58891727-58910829 protein_coding
  ENST00000306120 GNAS-050 58853456-58855333 protein_coding
  ENST00000313949 GNAS-002 58839718-58911192 protein_coding
  ENST00000338783 GNAS-021 58891760-58900410 protein_coding
  ENST00000349036 GNAS-037 58855147-58905480 protein_coding
  ENST00000354359 GNAS-018 58891303-58911192 protein_coding
  ENST00000371075 GNAS-014 58839748-58911192 protein_coding
  ENST00000371081 GNAS-038 58891716-58900410 protein_coding
  ENST00000371085 GNAS-015 58891303-58911192 protein_coding
  ENST00000371095 GNAS-017 58891302-58911192 protein_coding
  ENST00000371098 GNAS-025 58839748-58900410 protein_coding
  ENST00000371099 GNAS-058 58853263-58857191 protein_coding
  ENST00000371100 GNAS-001 58852714-58911192 protein_coding
  ENST00000371102 GNAS-009 58853263-58911192 protein_coding
  ENST00000419558 GNAS-023 58840504-58905480 protein_coding
  ENST00000423897 GNAS-049 58855178-58900410 protein_coding
  ENST00000450130 GNAS-036 58855107-58909183 protein_coding
  ENST00000453292 GNAS-022 58840344-58903543 protein_coding
  ENST00000461152 GNAS-056 58890643-58903585 processed_transcript
  ENST00000462499 GNAS-032 58841618-58903774 processed_transcript
  ENST00000464624 GNAS-059 58853263-58911192 processed_transcript
  ENST00000464788 GNAS-054 58889147-58909419 processed_transcript
  ENST00000464960 GNAS-040 58888413-58900410 processed_transcript
  ENST00000467227 GNAS-034 58843325-58909366 processed_transcript
  ENST00000467321 GNAS-053 58888893-58909579 processed_transcript
  ENST00000468895 GNAS-052 58888859-58909575 processed_transcript
  ENST00000469431 GNAS-011 58889151-58909216 processed_transcript
  ENST00000470512 GNAS-006 58889144-58909804 processed_transcript
  ENST00000472183 GNAS-027 58841485-58909423 processed_transcript
  ENST00000475610 GNAS-044 58910008-58910781 retained_intron
  ENST00000476196 GNAS-041 58902981-58911190 retained_intron
  ENST00000476935 GNAS-030 58892037-58909804 processed_transcript
  ENST00000477931 GNAS-016 58889100-58911192 processed_transcript
  ENST00000478585 GNAS-008 58889160-58905480 processed_transcript
  ENST00000479025 GNAS-045 58908916-58909715 retained_intron
  ENST00000480232 GNAS-055 58889223-58909985 processed_transcript
  ENST00000480975 GNAS-007 58889171-58911179 processed_transcript
  ENST00000481039 GNAS-004 58888849-58909804 processed_transcript
  ENST00000481768 GNAS-012 58854169-58900410 processed_transcript
  ENST00000482112 GNAS-031 58841618-58909394 processed_transcript
  ENST00000483387 GNAS-047 58895163-58903556 retained_intron
  ENST00000484504 GNAS-046 58889227-58900410 processed_transcript
  ENST00000485673 GNAS-005 58889124-58905420 processed_transcript
  ENST00000487862 GNAS-019 58895197-58911192 retained_intron
  ENST00000487981 GNAS-057 58903537-58909712 retained_intron
  ENST00000488546 GNAS-003 58888779-58910401 processed_transcript
  ENST00000488652 GNAS-029 58891981-58909974 processed_transcript
  ENST00000490374 GNAS-033 58841622-58909188 processed_transcript
  ENST00000491348 GNAS-026 58841343-58900410 processed_transcript
  ENST00000492907 GNAS-013 58892078-58909804 processed_transcript
  ENST00000493744 GNAS-048 58841644-58900410 processed_transcript
  ENST00000493958 GNAS-043 58903741-58909776 processed_transcript
  ENST00000494081 GNAS-042 58903531-58910365 processed_transcript
  ENST00000496934 GNAS-020 58897440-58911192 retained_intron
  ENST00000603546 GNAS-063 58892333-58909169 protein_coding
  ENST00000604005 GNAS-071 58889160-58909423 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000265620ENST00000306090ENST00000354359ENST00000371085ENST00000371095ENST00000476196ENST00000477931ENST00000480975ENST00000481039ENST00000487862ENST00000488546
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000265620 46.116±0.00 73.198±55.86 179.631±0.00 112.734±45.49
ENST00000306090 615.657±0.00 N/A N/A 388.948±0.00
ENST00000354359 N/A N/A N/A 37.128±0.00
ENST00000371085 102.201±0.00 118.132±52.65 N/A 156.310±108.64
ENST00000371095 N/A 20.124±0.09 N/A 120.568±67.29
ENST00000476196 N/A N/A N/A 27.115±16.73
ENST00000477931 N/A N/A N/A 88.388±0.00
ENST00000480975 N/A N/A N/A 223.681±154.28
ENST00000481039 N/A 166.411±0.00 N/A 204.082±45.41
ENST00000487862 N/A N/A N/A 79.613±31.30
ENST00000488546 N/A N/A N/A 385.572±8.75

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00073J CIL_00073J_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 IEA skeletal system development
GO:0001894 IEA tissue homeostasis
GO:0001958 IEA endochondral ossification
GO:0003674 ND molecular_function
GO:0003924 TAS:IEA GTPase activity
GO:0004016 TAS adenylate cyclase activity
GO:0004871 IDA:IEA signal transducer activity
GO:0005159 IBA insulin-like growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005576 IEA extracellular region
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0005834 ISS heterotrimeric G-protein complex
GO:0005886 TAS plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0006171 TAS cAMP biosynthetic process
GO:0006184 IEA GTP catabolic process
GO:0006306 IEA DNA methylation
GO:0006833 TAS water transport
GO:0007165 IEA signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007189 IDA adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190 TAS activation of adenylate cyclase activity
GO:0007191 ISS adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007565 NAS female pregnancy
GO:0007596 TAS blood coagulation
GO:0007606 IBA sensory perception of chemical stimulus
GO:0007608 TAS sensory perception of smell
GO:0009306 NAS protein secretion
GO:0009791 IEA post-embryonic development
GO:0016020 IDA membrane
GO:0019001 IEA guanyl nucleotide binding
GO:0030425 IEA dendrite
GO:0030819 IDA positive regulation of cAMP biosynthetic process
GO:0031224 IDA intrinsic component of membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0031683 IEA G-protein beta/gamma-subunit complex binding
GO:0031698 IBA beta-2 adrenergic receptor binding
GO:0031748 IBA D1 dopamine receptor binding
GO:0031852 IBA mu-type opioid receptor binding
GO:0032320 IDA positive regulation of Ras GTPase activity
GO:0032588 IDA trans-Golgi network membrane
GO:0035116 IEA embryonic hindlimb morphogenesis
GO:0035255 IBA ionotropic glutamate receptor binding
GO:0035264 IEA multicellular organism growth
GO:0040015 ISS negative regulation of multicellular organism growth
GO:0040032 IEA post-embryonic body morphogenesis
GO:0042493 IEA response to drug
GO:0042995 IEA cell projection
GO:0043588 IEA skin development
GO:0043950 IDA positive regulation of cAMP-mediated signaling
GO:0044281 TAS small molecule metabolic process
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0045672 IEA positive regulation of osteoclast differentiation
GO:0046872 IEA metal ion binding
GO:0046907 NAS intracellular transport
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048589 IDA developmental growth
GO:0048701 IEA embryonic cranial skeleton morphogenesis
GO:0050796 TAS regulation of insulin secretion
GO:0050890 IDA cognition
GO:0051216 IEA cartilage development
GO:0051430 IBA corticotropin-releasing hormone receptor 1 binding
GO:0055085 TAS transmembrane transport
GO:0060348 IDA bone development
GO:0060789 IDA hair follicle placode formation
GO:0070062 IDA extracellular vesicular exosome
GO:0070527 IDA platelet aggregation
GO:0071107 IMP response to parathyroid hormone
GO:0071377 TAS cellular response to glucagon stimulus
GO:0071380 ISS cellular response to prostaglandin E stimulus
GO:0071514 IEA genetic imprinting
GO:0071870 ISS cellular response to catecholamine stimulus
GO:0071880 IDA adenylate cyclase-activating adrenergic receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043094 gnas protein_coding Danio_rerio
ENSMUSG00000027523 Gnas protein_coding Mus_musculus

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