ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: GNAS complex locus
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000265620 GNAS-035 ENSG00000087460 9606 + 20:58891364-58911192 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000265620
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000265620 46.116±0.00 73.198±55.86 179.631±0.00 112.734±45.49

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003924 TAS:IEA GTPase activity
GO:0004016 TAS adenylate cyclase activity
GO:0004871 IDA:IEA signal transducer activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0005834 ISS heterotrimeric G-protein complex
GO:0005886 TAS plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0006171 TAS cAMP biosynthetic process
GO:0006184 IEA GTP catabolic process
GO:0006833 TAS water transport
GO:0007165 IEA signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007189 IDA adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190 TAS activation of adenylate cyclase activity
GO:0007191 ISS adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007596 TAS blood coagulation
GO:0007608 TAS sensory perception of smell
GO:0016020 IDA membrane
GO:0019001 IEA guanyl nucleotide binding
GO:0030819 IDA positive regulation of cAMP biosynthetic process
GO:0031224 IDA intrinsic component of membrane
GO:0031683 IEA G-protein beta/gamma-subunit complex binding
GO:0032320 IDA positive regulation of Ras GTPase activity
GO:0032588 IDA trans-Golgi network membrane
GO:0043950 IDA positive regulation of cAMP-mediated signaling
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0046907 NAS intracellular transport
GO:0048589 IDA developmental growth
GO:0050796 TAS regulation of insulin secretion
GO:0050890 IDA cognition
GO:0055085 TAS transmembrane transport
GO:0060348 IDA bone development
GO:0060789 IDA hair follicle placode formation
GO:0070062 IDA extracellular vesicular exosome
GO:0070527 IDA platelet aggregation
GO:0071377 TAS cellular response to glucagon stimulus
GO:0071380 ISS cellular response to prostaglandin E stimulus
GO:0071870 ISS cellular response to catecholamine stimulus
GO:0071880 IDA adenylate cyclase-activating adrenergic receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000109084 Gnas-017 protein_coding Mus_musculus 0 2252
ENSMUST00000109085 Gnas-014 protein_coding Mus_musculus 0 2237
ENSMUST00000087876 Gnas-020 protein_coding Mus_musculus 0 1965
ENSMUST00000087871 Gnas-002 protein_coding Mus_musculus 0 1831
ENSMUST00000109096 Gnas-007 protein_coding Mus_musculus 0 1831
ENSMUST00000109087 Gnas-201 protein_coding Mus_musculus 0 1803
ENSMUST00000186907 Gnas-204 protein_coding Mus_musculus 0 1803
ENSMUST00000185956 Gnas-203 protein_coding Mus_musculus 0 1803
ENSMUST00000168292 Gm20721-201 protein_coding Mus_musculus 0 1792
ENSMUST00000156623 Gnas-001 processed_transcript Mus_musculus 0 1576
ENSMUST00000109088 Gnas-019 protein_coding Mus_musculus 0 1576
ENSMUST00000154658 Gnas-005 processed_transcript Mus_musculus 0 1576
ENSMUST00000080493 Gnas-004 protein_coding Mus_musculus 0 1576
ENSMUST00000130940 Gnas-009 protein_coding Mus_musculus 0 869
ENSMUST00000129534 Gnas-012 retained_intron Mus_musculus 0 603
ENSMUST00000148640 Gnas-016 processed_transcript Mus_musculus 0 575
ENSMUST00000131125 Gnas-011 retained_intron Mus_musculus 0 569
ENSMUST00000124935 Gnas-015 processed_transcript Mus_musculus 0 510
ENSMUST00000109083 Gnas-018 protein_coding Mus_musculus 0 381
ENSMUST00000133356 Gnas-010 processed_transcript Mus_musculus 9e-26 122
ENSMUST00000180362 Gnas-202 protein_coding Mus_musculus 3e-25 121
ENSMUST00000130761 Gnas-013 protein_coding Mus_musculus 3e-25 121

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