ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000088256 GNA11 9606 + 19:3094410-3124004 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000078429 GNA11-001 3094410-3124004 protein_coding
  ENST00000586180 GNA11-004 3118696-3121319 processed_transcript
  ENST00000586763 GNA11-005 3094649-3115003 processed_transcript
  ENST00000587636 GNA11-007 3113463-3121457 protein_coding
  ENST00000588401 GNA11-003 3114947-3115428 protein_coding
  ENST00000590534 GNA11-002 3117150-3121454 retained_intron
  ENST00000591301 GNA11-006 3118813-3119353 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000078429ENST00000587636ENST00000590534
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000078429 4.428±0.00 18.366±6.94 9.982±0.00 15.390±13.15
ENST00000587636 N/A 45.695±9.62 N/A 8.808±8.15
ENST00000590534 N/A N/A N/A 0.847±0.72

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005QO CIL_0005QO_0003 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 IEA skeletal system development
GO:0001508 IBA action potential
GO:0003924 IBA:IEA GTPase activity
GO:0004871 IBA:IEA signal transducer activity
GO:0005525 IEA GTP binding
GO:0005737 TAS cytoplasm
GO:0005765 IDA lysosomal membrane
GO:0005834 IBA heterotrimeric G-protein complex
GO:0005886 TAS plasma membrane
GO:0006184 IEA GTP catabolic process
GO:0007165 TAS:IEA signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007188 IBA adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007507 IEA heart development
GO:0007596 TAS blood coagulation
GO:0019001 IEA guanyl nucleotide binding
GO:0030168 TAS platelet activation
GO:0031683 IBA:IEA G-protein beta/gamma-subunit complex binding
GO:0031826 IBA type 2A serotonin receptor binding
GO:0045634 IEA regulation of melanocyte differentiation
GO:0046872 IEA metal ion binding
GO:0048066 IEA developmental pigmentation
GO:0060158 IBA phospholipase C-activating dopamine receptor signaling pathway
GO:0070062 IDA extracellular vesicular exosome
GO:0071467 IEA cellular response to pH

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010002 gna11a protein_coding Danio_rerio
ENSDARG00000053326 gna11b protein_coding Danio_rerio
ENSMUSG00000034781 Gna11 protein_coding Mus_musculus

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