ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000078429 GNA11-001 ENSG00000088256 9606 + 19:3094410-3124004 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000078429
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000078429 4.428±0.00 18.366±6.94 9.982±0.00 15.390±13.15

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001501 IEA skeletal system development
GO:0001508 IBA action potential
GO:0003924 IBA:IEA GTPase activity
GO:0004871 IBA:IEA signal transducer activity
GO:0005525 IEA GTP binding
GO:0005737 TAS cytoplasm
GO:0005765 IDA lysosomal membrane
GO:0005834 IBA heterotrimeric G-protein complex
GO:0005886 TAS plasma membrane
GO:0006184 IEA GTP catabolic process
GO:0007165 TAS:IEA signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007188 IBA adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007507 IEA heart development
GO:0007596 TAS blood coagulation
GO:0019001 IEA guanyl nucleotide binding
GO:0030168 TAS platelet activation
GO:0031683 IBA:IEA G-protein beta/gamma-subunit complex binding
GO:0031826 IBA type 2A serotonin receptor binding
GO:0045634 IEA regulation of melanocyte differentiation
GO:0046872 IEA metal ion binding
GO:0048066 IEA developmental pigmentation
GO:0060158 IBA phospholipase C-activating dopamine receptor signaling pathway
GO:0070062 IDA extracellular vesicular exosome
GO:0071467 IEA cellular response to pH

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000043604 Gna11-001 protein_coding Mus_musculus 0 1397
ENSDART00000105566 gna11a-002 protein_coding Danio_rerio 0 966
ENSDART00000136795 gna11a-001 protein_coding Danio_rerio 0 905
ENSMUST00000025541 Gnaq-001 protein_coding Mus_musculus 0 850
ENSMUST00000146984 Gna11-002 retained_intron Mus_musculus 0 582
ENSMUST00000134354 Gna11-003 retained_intron Mus_musculus 0 220
ENSMUST00000055704 Gnai2-001 protein_coding Mus_musculus 4e-27 128
ENSMUST00000192615 Gnai2-003 protein_coding Mus_musculus 4e-27 128
ENSMUST00000195231 Gnai2-005 retained_intron Mus_musculus 0.00000000000003 86

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