ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: pleckstrin homology domain containing, family G (with RhoGef domain) member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000090924 PLEKHG2 9606 + 19:39412585-39428415 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000205135 PLEKHG2-003 39415193-39425739 protein_coding
  ENST00000409797 PLEKHG2-002 39413665-39425516 protein_coding
  ENST00000425673 PLEKHG2-001 39412585-39428415 protein_coding
  ENST00000438123 PLEKHG2-004 39413528-39415260 protein_coding
  ENST00000451354 PLEKHG2-006 39413812-39416597 protein_coding
  ENST00000458508 PLEKHG2-008 39413309-39425437 protein_coding
  ENST00000474449 PLEKHG2-007 39421666-39422828 retained_intron
  ENST00000478523 PLEKHG2-005 39417845-39421113 retained_intron
  ENST00000594124 PLEKHG2-016 39424771-39425665 protein_coding
  ENST00000594161 PLEKHG2-014 39424388-39425516 protein_coding
  ENST00000594307 PLEKHG2-011 39421035-39422216 retained_intron
  ENST00000595920 PLEKHG2-009 39413150-39414232 protein_coding
  ENST00000596339 PLEKHG2-015 39424563-39425495 protein_coding
  ENST00000596443 PLEKHG2-010 39420801-39425473 protein_coding
  ENST00000598238 PLEKHG2-013 39424311-39425514 protein_coding
  ENST00000600210 PLEKHG2-012 39423428-39425512 protein_coding

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000205135ENST00000409797ENST00000425673ENST00000458508ENST00000594161
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000205135 3.287±1.28 4.218±1.91 10.956±0.00 5.812±0.00 4.884±2.61
ENST00000409797 N/A N/A N/A N/A 4.063±0.00
ENST00000425673 2.659±0.00 0.601±0.12 N/A 4.177±0.00 2.950±1.61
ENST00000458508 N/A 1.153±0.36 N/A N/A 3.622±1.72
ENST00000594161 33.800±0.00 N/A N/A N/A N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005829 TAS cytosol
GO:0007264 TAS small GTPase mediated signal transduction
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0043065 TAS positive regulation of apoptotic process
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058459 plekhg2 protein_coding Danio_rerio
ENSMUSG00000037552 Plekhg2 protein_coding Mus_musculus

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