ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: pleckstrin homology domain containing, family G (with RhoGef domain) member 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000425673 PLEKHG2-001 ENSG00000090924 9606 + 19:39412585-39428415 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000425673
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000425673 2.659±0.00 0.601±0.12 4.177±0.00 2.950±1.61

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005829 TAS cytosol
GO:0007264 TAS small GTPase mediated signal transduction
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0043065 TAS positive regulation of apoptotic process
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000119990 Plekhg2-001 protein_coding Mus_musculus 0 2191
ENSMUST00000094644 Plekhg2-004 protein_coding Mus_musculus 0 2176
ENSMUST00000144700 Plekhg2-002 protein_coding Mus_musculus 0 2134
ENSMUST00000128015 Plekhg2-003 retained_intron Mus_musculus 0 2076
ENSMUST00000121085 Plekhg2-005 protein_coding Mus_musculus 0 1380
ENSMUST00000147362 Plekhg2-008 protein_coding Mus_musculus 0 536
ENSMUST00000147767 Plekhg2-010 retained_intron Mus_musculus 0 351
ENSMUST00000152281 Plekhg2-007 nonsense_mediated_decay Mus_musculus 0 278

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