ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: bone morphogenetic protein 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101144 BMP7 9606 - 20:57168748-57266629 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000395863 BMP7-001 57168748-57266628 protein_coding
  ENST00000395864 BMP7-003 57170531-57266342 protein_coding
  ENST00000433911 BMP7-004 57173220-57265778 protein_coding
  ENST00000450594 BMP7-002 57172996-57266629 protein_coding
  ENST00000460817 BMP7-005 57171039-57224685 processed_transcript
  ENST00000463939 BMP7-006 57177696-57187156 processed_transcript
  ENST00000476877 BMP7-007 57170917-57173589 retained_intron
  ENST00000524700 BMP7-009 57202474-57224840 processed_transcript
  ENST00000530870 BMP7-008 57202474-57244034 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHMVEC-DHUVECENST00000395863ENST00000395864ENST00000433911ENST00000450594ENST00000460817ENST00000476877
Transcript ID HAoEC HHSEC HMVEC-D HUVEC
ENST00000395863 0.044±0.02 0.087±0.00 0.036±0.00 0.040±0.02
ENST00000395864 0.119±0.02 N/A N/A N/A
ENST00000433911 0.126±0.04 N/A N/A N/A
ENST00000450594 0.038±0.03 N/A N/A N/A
ENST00000460817 0.144±0.01 N/A N/A N/A
ENST00000476877 0.159±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000339 CIL_000339_0001 CGP
CIL_0008YW CIL_0008YW_0001 VISTA
CIL_0008TD CIL_0008TD_0001 VISTA
CIL_0008HJ CIL_0008HJ_0001 VISTA
CIL_0008BA CIL_0008BA_0001 VISTA
CIL_0006IN CIL_0006IN_0002 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001501 TAS skeletal system development
GO:0001503 IEA ossification
GO:0001654 IEA eye development
GO:0001656 IEP metanephros development
GO:0001657 ISS ureteric bud development
GO:0001707 IEA mesoderm formation
GO:0001822 IEA kidney development
GO:0001823 IEP mesonephros development
GO:0001837 TAS epithelial to mesenchymal transition
GO:0005125 IEA cytokine activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0007389 IEA pattern specification process
GO:0007411 IEA axon guidance
GO:0007435 IEA salivary gland morphogenesis
GO:0008083 IEA growth factor activity
GO:0008201 IEA heparin binding
GO:0008285 IEA negative regulation of cell proliferation
GO:0009880 IEA embryonic pattern specification
GO:0009887 IEA organ morphogenesis
GO:0010664 ISS negative regulation of striated muscle cell apoptotic process
GO:0010800 IDA positive regulation of peptidyl-threonine phosphorylation
GO:0010862 TAS positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0010942 IEA positive regulation of cell death
GO:0016358 TAS dendrite development
GO:0030198 TAS extracellular matrix organization
GO:0030326 IEA embryonic limb morphogenesis
GO:0030501 IDA positive regulation of bone mineralization
GO:0030509 IDA BMP signaling pathway
GO:0030855 IEA epithelial cell differentiation
GO:0031012 IEA extracellular matrix
GO:0031988 IEA membrane-bounded vesicle
GO:0032088 ISS negative regulation of NF-kappaB transcription factor activity
GO:0032355 IEA response to estradiol
GO:0033280 IEA response to vitamin D
GO:0034116 IDA positive regulation of heterotypic cell-cell adhesion
GO:0034504 IDA protein localization to nucleus
GO:0035239 IEA tube morphogenesis
GO:0040007 IEA growth
GO:0042325 IEA regulation of phosphorylation
GO:0042326 IDA negative regulation of phosphorylation
GO:0042347 ISS negative regulation of NF-kappaB import into nucleus
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0043065 IEA positive regulation of apoptotic process
GO:0043401 IMP steroid hormone mediated signaling pathway
GO:0043407 IDA negative regulation of MAP kinase activity
GO:0043434 IEA response to peptide hormone
GO:0045597 IEA positive regulation of cell differentiation
GO:0045665 IDA negative regulation of neuron differentiation
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045669 IDA positive regulation of osteoblast differentiation
GO:0045746 IEA negative regulation of Notch signaling pathway
GO:0045786 IDA negative regulation of cell cycle
GO:0045839 IDA negative regulation of mitosis
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048468 IEA cell development
GO:0048593 IEA camera-type eye morphogenesis
GO:0048596 IEA embryonic camera-type eye morphogenesis
GO:0048646 IEA anatomical structure formation involved in morphogenesis
GO:0048754 IEA branching morphogenesis of an epithelial tube
GO:0048762 IDA mesenchymal cell differentiation
GO:0048812 IDA neuron projection morphogenesis
GO:0050768 IEA negative regulation of neurogenesis
GO:0051216 IEA cartilage development
GO:0060272 IEA embryonic skeletal joint morphogenesis
GO:0060393 IDA regulation of pathway-restricted SMAD protein phosphorylation
GO:0060395 IDA SMAD protein signal transduction
GO:0060445 IEA branching involved in salivary gland morphogenesis
GO:0060485 ISS mesenchyme development
GO:0060548 IDA negative regulation of cell death
GO:0060686 IEA negative regulation of prostatic bud formation
GO:0060687 IEA regulation of branching involved in prostate gland morphogenesis
GO:0070487 IDA monocyte aggregation
GO:0071456 ISS cellular response to hypoxia
GO:0072040 IEA negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
GO:0072125 IDA negative regulation of glomerular mesangial cell proliferation
GO:0072133 IEA metanephric mesenchyme morphogenesis
GO:0072134 IEA nephrogenic mesenchyme morphogenesis
GO:0072136 IEA metanephric mesenchymal cell proliferation involved in metanephros development
GO:1900006 IDA positive regulation of dendrite development
GO:1900106 IDA positive regulation of hyaluranon cable assembly
GO:2000121 ISS regulation of removal of superoxide radicals

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018260 bmp7a protein_coding Danio_rerio
ENSDARG00000063230 bmp7b protein_coding Danio_rerio
ENSMUSG00000008999 Bmp7 protein_coding Mus_musculus

Loading