ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: bone morphogenetic protein 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000395863 BMP7-001 ENSG00000101144 9606 - 20:57168748-57266628 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHMVEC-DHUVECENST00000395863
Transcript ID HAoEC HHSEC HMVEC-D HUVEC
ENST00000395863 0.044±0.02 0.087±0.00 0.036±0.00 0.040±0.02

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001501 TAS skeletal system development
GO:0001503 IEA ossification
GO:0001654 IEA eye development
GO:0001656 IEP metanephros development
GO:0001657 ISS ureteric bud development
GO:0001707 IEA mesoderm formation
GO:0001822 IEA kidney development
GO:0001823 IEP mesonephros development
GO:0001837 TAS epithelial to mesenchymal transition
GO:0005125 IEA cytokine activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0007389 IEA pattern specification process
GO:0007411 IEA axon guidance
GO:0007435 IEA salivary gland morphogenesis
GO:0008083 IEA growth factor activity
GO:0008201 IEA heparin binding
GO:0008285 IEA negative regulation of cell proliferation
GO:0009880 IEA embryonic pattern specification
GO:0009887 IEA organ morphogenesis
GO:0010664 ISS negative regulation of striated muscle cell apoptotic process
GO:0010800 IDA positive regulation of peptidyl-threonine phosphorylation
GO:0010862 TAS positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0010942 IEA positive regulation of cell death
GO:0016358 TAS dendrite development
GO:0030198 TAS extracellular matrix organization
GO:0030326 IEA embryonic limb morphogenesis
GO:0030501 IDA positive regulation of bone mineralization
GO:0030509 IDA BMP signaling pathway
GO:0030855 IEA epithelial cell differentiation
GO:0031012 IEA extracellular matrix
GO:0031988 IEA membrane-bounded vesicle
GO:0032088 ISS negative regulation of NF-kappaB transcription factor activity
GO:0032355 IEA response to estradiol
GO:0033280 IEA response to vitamin D
GO:0034116 IDA positive regulation of heterotypic cell-cell adhesion
GO:0034504 IDA protein localization to nucleus
GO:0035239 IEA tube morphogenesis
GO:0040007 IEA growth
GO:0042325 IEA regulation of phosphorylation
GO:0042326 IDA negative regulation of phosphorylation
GO:0042347 ISS negative regulation of NF-kappaB import into nucleus
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0043065 IEA positive regulation of apoptotic process
GO:0043401 IMP steroid hormone mediated signaling pathway
GO:0043407 IDA negative regulation of MAP kinase activity
GO:0043434 IEA response to peptide hormone
GO:0045597 IEA positive regulation of cell differentiation
GO:0045665 IDA negative regulation of neuron differentiation
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045669 IDA positive regulation of osteoblast differentiation
GO:0045746 IEA negative regulation of Notch signaling pathway
GO:0045786 IDA negative regulation of cell cycle
GO:0045839 IDA negative regulation of mitosis
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048468 IEA cell development
GO:0048593 IEA camera-type eye morphogenesis
GO:0048596 IEA embryonic camera-type eye morphogenesis
GO:0048646 IEA anatomical structure formation involved in morphogenesis
GO:0048754 IEA branching morphogenesis of an epithelial tube
GO:0048762 IDA mesenchymal cell differentiation
GO:0048812 IDA neuron projection morphogenesis
GO:0050768 IEA negative regulation of neurogenesis
GO:0051216 IEA cartilage development
GO:0060272 IEA embryonic skeletal joint morphogenesis
GO:0060393 IDA regulation of pathway-restricted SMAD protein phosphorylation
GO:0060395 IDA SMAD protein signal transduction
GO:0060445 IEA branching involved in salivary gland morphogenesis
GO:0060485 ISS mesenchyme development
GO:0060548 IDA negative regulation of cell death
GO:0060686 IEA negative regulation of prostatic bud formation
GO:0060687 IEA regulation of branching involved in prostate gland morphogenesis
GO:0070487 IDA monocyte aggregation
GO:0071456 ISS cellular response to hypoxia
GO:0072040 IEA negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
GO:0072125 IDA negative regulation of glomerular mesangial cell proliferation
GO:0072133 IEA metanephric mesenchyme morphogenesis
GO:0072134 IEA nephrogenic mesenchyme morphogenesis
GO:0072136 IEA metanephric mesenchymal cell proliferation involved in metanephros development
GO:1900006 IDA positive regulation of dendrite development
GO:1900106 IDA positive regulation of hyaluranon cable assembly
GO:2000121 ISS regulation of removal of superoxide radicals

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000009143 Bmp7-001 protein_coding Mus_musculus 0 1906
ENSMUST00000137247 Bmp7-002 retained_intron Mus_musculus 0 850
ENSDART00000092214 bmp7b-201 protein_coding Danio_rerio 0 758
ENSDART00000138020 bmp7b-001 protein_coding Danio_rerio 0 758
ENSMUST00000121101 Rspry1-002 protein_coding Mus_musculus 0.00007 55

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