ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: CCCTC-binding factor (zinc finger protein)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000102974 CTCF 9606 + 16:67562407-67639183 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264010 CTCF-001 67562407-67639183 protein_coding
  ENST00000401394 CTCF-002 67562407-67639183 protein_coding
  ENST00000566078 CTCF-003 67562538-67612146 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000264010ENST00000401394
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000264010 0.690±0.38 9.156±3.70 N/A 12.449±0.00 8.329±4.08
ENST00000401394 3.757±0.75 N/A 2.580±0.00 N/A 1.500±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003LR CIL_0003LR_0002 CGP
CIL_0006LW CIL_0006LW_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000775 IDA chromosome, centromeric region
GO:0000793 IDA condensed chromosome
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003714 TAS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005730 IDA nucleolus
GO:0006306 IEA DNA methylation
GO:0006349 IEA regulation of gene expression by genetic imprinting
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007059 IEA chromosome segregation
GO:0008270 TAS zinc ion binding
GO:0010216 IEA maintenance of DNA methylation
GO:0010628 IMP positive regulation of gene expression
GO:0010629 IEA negative regulation of gene expression
GO:0016568 IEA chromatin modification
GO:0016584 IDA nucleosome positioning
GO:0031060 IEA regulation of histone methylation
GO:0035065 IEA regulation of histone acetylation
GO:0040029 IMP regulation of gene expression, epigenetic
GO:0040030 IMP regulation of molecular function, epigenetic
GO:0043035 IDA chromatin insulator sequence binding
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0070602 NAS regulation of centromeric sister chromatid cohesion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056621 ctcf protein_coding Danio_rerio
ENSMUSG00000005698 Ctcf protein_coding Mus_musculus

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