ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: Rho guanine nucleotide exchange factor (GEF) 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104728 ARHGEF10 9606 + 8:1823976-1958641 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000349830 ARHGEF10-003 1823976-1958633 protein_coding
  ENST00000382795 ARHGEF10-008 1858755-1869280 processed_transcript
  ENST00000398560 ARHGEF10-201 1858755-1904096 protein_coding
  ENST00000398564 ARHGEF10-202 1826111-1958633 protein_coding
  ENST00000518288 ARHGEF10-001 1824015-1958641 protein_coding
  ENST00000519641 ARHGEF10-010 1923196-1923874 retained_intron
  ENST00000520359 ARHGEF10-002 1823988-1958641 protein_coding
  ENST00000520972 ARHGEF10-006 1859894-1904110 retained_intron
  ENST00000521927 ARHGEF10-013 1943654-1957205 processed_transcript
  ENST00000522435 ARHGEF10-004 1882656-1958639 protein_coding
  ENST00000522969 ARHGEF10-007 1859915-1871131 retained_intron
  ENST00000523596 ARHGEF10-012 1943594-1952774 processed_transcript
  ENST00000523711 ARHGEF10-005 1876051-1927513 retained_intron
  ENST00000523980 ARHGEF10-011 1943595-1945919 retained_intron
  ENST00000524212 ARHGEF10-009 1904235-1923490 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000349830ENST00000382795ENST00000398564ENST00000520359ENST00000520972ENST00000522435ENST00000522969ENST00000523711
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000349830 N/A 3.535±1.08 2.173±0.00 3.604±1.66
ENST00000382795 N/A N/A N/A 2.933±0.00
ENST00000398564 N/A 6.053±1.60 5.983±0.00 2.508±1.48
ENST00000520359 0.902±0.00 6.892±1.68 3.740±0.00 6.377±3.68
ENST00000520972 N/A N/A N/A 0.765±0.00
ENST00000522435 N/A 3.108±0.42 4.093±0.00 3.328±0.87
ENST00000522969 N/A N/A N/A 0.803±0.09
ENST00000523711 N/A N/A N/A 0.608±0.08

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007GL CIL_0007GL_0002 CGP
CIL_0000LF CIL_0000LF_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IDA:IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI:IEA protein binding
GO:0005813 IDA centrosome
GO:0005829 NAS cytosol
GO:0019894 IPI kinesin binding
GO:0022011 IMP myelination in peripheral nervous system
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0033126 IDA positive regulation of GTP catabolic process
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0051298 IMP centrosome duplication
GO:0051496 IMP positive regulation of stress fiber assembly
GO:0090307 IMP spindle assembly involved in mitosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077788 arhgef10 protein_coding Danio_rerio
ENSMUSG00000071176 Arhgef10 protein_coding Mus_musculus

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