ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: DENN/MADD domain containing 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105339 DENND3 9606 + 8:141117278-141195808 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262585 DENND3-201 141128621-141195796 protein_coding
  ENST00000424248 DENND3-202 141136626-141195511 protein_coding
  ENST00000517813 DENND3-006 141184488-141195807 retained_intron
  ENST00000517985 DENND3-015 141178121-141185458 protein_coding
  ENST00000518198 DENND3-003 141128621-141142511 nonsense_mediated_decay
  ENST00000518249 DENND3-016 141141203-141143008 protein_coding
  ENST00000518347 DENND3-011 141128612-141141455 protein_coding
  ENST00000518668 DENND3-002 141128779-141195808 protein_coding
  ENST00000518806 DENND3-020 141177087-141185223 processed_transcript
  ENST00000519291 DENND3-010 141117278-141141276 protein_coding
  ENST00000519811 DENND3-001 141128638-141195808 protein_coding
  ENST00000520482 DENND3-005 141157395-141176266 retained_intron
  ENST00000520571 DENND3-009 141188898-141190624 retained_intron
  ENST00000520725 DENND3-014 141192331-141193070 protein_coding
  ENST00000520986 DENND3-012 141128649-141151837 protein_coding
  ENST00000521477 DENND3-018 141155894-141166233 processed_transcript
  ENST00000521835 DENND3-008 141191274-141195799 retained_intron
  ENST00000523015 DENND3-017 141143914-141150889 retained_intron
  ENST00000523058 DENND3-021 141128675-141150908 protein_coding
  ENST00000523066 DENND3-019 141173505-141176652 processed_transcript
  ENST00000523308 DENND3-007 141188349-141195802 protein_coding
  ENST00000523530 DENND3-013 141191274-141192901 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000262585ENST00000424248ENST00000517813ENST00000518668ENST00000519811ENST00000520482ENST00000521835ENST00000523308ENST00000523530
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000262585 N/A 3.083±1.07 N/A N/A 2.483±0.63
ENST00000424248 N/A 4.717±2.00 N/A N/A 4.119±2.70
ENST00000517813 1.117±0.00 N/A N/A N/A 6.359±4.80
ENST00000518668 1.201±0.00 6.649±3.60 0.981±0.00 N/A 2.218±0.00
ENST00000519811 N/A 5.277±3.75 N/A 14.134±0.00 6.717±2.82
ENST00000520482 N/A 3.410±0.69 N/A N/A 3.109±1.44
ENST00000521835 N/A N/A 1.350±0.00 N/A 2.570±0.00
ENST00000523308 9.851±0.00 N/A 3.502±0.00 N/A 5.809±0.00
ENST00000523530 N/A N/A N/A N/A 3.279±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0006FQ CIL_0006FQ_0002 CGP
CIL_0007WG CIL_0007WG_0001 VISTA
CIL_0000X9 CIL_0000X9_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0008333 ISS endosome to lysosome transport
GO:0017112 IDA Rab guanyl-nucleotide exchange factor activity
GO:0032851 IDA positive regulation of Rab GTPase activity
GO:0044257 ISS cellular protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013153 dennd3b protein_coding Danio_rerio
ENSDARG00000078797 dennd3a protein_coding Danio_rerio
ENSMUSG00000036661 Dennd3 protein_coding Mus_musculus

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