ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: phospholipase A2, group IVC (cytosolic, calcium-independent)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105499 PLA2G4C 9606 - 19:48047843-48110817 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000354276 PLA2G4C-005 48047844-48110782 protein_coding
  ENST00000593765 PLA2G4C-021 48074438-48085110 retained_intron
  ENST00000594156 PLA2G4C-011 48099798-48110813 processed_transcript
  ENST00000594790 PLA2G4C-006 48047846-48055059 retained_intron
  ENST00000595161 PLA2G4C-024 48061360-48074837 protein_coding
  ENST00000595487 PLA2G4C-007 48099744-48110561 nonsense_mediated_decay
  ENST00000595899 PLA2G4C-014 48099772-48110563 processed_transcript
  ENST00000596138 PLA2G4C-009 48105334-48110746 protein_coding
  ENST00000596352 PLA2G4C-010 48099782-48110563 protein_coding
  ENST00000596353 PLA2G4C-023 48054890-48067931 retained_intron
  ENST00000596510 PLA2G4C-003 48051797-48073051 processed_transcript
  ENST00000597377 PLA2G4C-015 48097022-48100006 retained_intron
  ENST00000597713 PLA2G4C-016 48095464-48098237 nonsense_mediated_decay
  ENST00000598185 PLA2G4C-019 48074846-48090603 retained_intron
  ENST00000598457 PLA2G4C-018 48090194-48099757 retained_intron
  ENST00000598488 PLA2G4C-008 48105403-48110563 nonsense_mediated_decay
  ENST00000598813 PLA2G4C-013 48103420-48110563 processed_transcript
  ENST00000599063 PLA2G4C-002 48097765-48110767 retained_intron
  ENST00000599111 PLA2G4C-001 48047843-48110817 protein_coding
  ENST00000599239 PLA2G4C-022 48061632-48096937 processed_transcript
  ENST00000599300 PLA2G4C-020 48054922-48090409 protein_coding
  ENST00000599921 PLA2G4C-004 48048343-48110812 protein_coding
  ENST00000600170 PLA2G4C-012 48104032-48105481 retained_intron
  ENST00000601946 PLA2G4C-017 48062122-48098208 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000354276ENST00000594156ENST00000594790ENST00000597377ENST00000597713ENST00000598813ENST00000599111ENST00000599239ENST00000599300ENST00000599921ENST00000601946
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000354276 N/A 1.444±0.26 N/A 11.848±0.00 4.756±2.57
ENST00000594156 N/A 3.102±1.50 N/A N/A 16.084±11.02
ENST00000594790 63.991±1.33 3.573±1.93 9.573±0.00 22.875±0.00 21.716±15.44
ENST00000597377 N/A 1.882±0.10 N/A N/A 3.792±0.00
ENST00000597713 N/A N/A N/A N/A 0.083±0.00
ENST00000598813 N/A N/A N/A N/A 0.077±0.00
ENST00000599111 N/A 0.682±0.24 N/A N/A 3.170±1.76
ENST00000599239 33.629±0.00 N/A N/A N/A 5.657±0.00
ENST00000599300 43.604±0.00 N/A N/A N/A N/A
ENST00000599921 N/A 2.248±1.21 N/A 12.898±0.00 11.907±11.49
ENST00000601946 N/A 2.663±1.01 N/A N/A N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004620 IEA phospholipase activity
GO:0005543 NAS phospholipid binding
GO:0005635 IEA nuclear envelope
GO:0005654 IEA nucleoplasm
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005829 TAS cytosol
GO:0005938 IEA cell cortex
GO:0006644 TAS phospholipid metabolic process
GO:0006954 NAS inflammatory response
GO:0007567 NAS parturition
GO:0008152 IEA metabolic process
GO:0009395 IEA phospholipid catabolic process
GO:0016020 TAS membrane
GO:0019369 NAS arachidonic acid metabolic process
GO:0035556 NAS intracellular signal transduction
GO:0036149 TAS phosphatidylinositol acyl-chain remodeling
GO:0036151 TAS phosphatidylcholine acyl-chain remodeling
GO:0036152 TAS phosphatidylethanolamine acyl-chain remodeling
GO:0044281 TAS small molecule metabolic process
GO:0046474 TAS glycerophospholipid biosynthetic process
GO:0046475 IDA glycerophospholipid catabolic process
GO:0047499 IDA calcium-independent phospholipase A2 activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033355 PLA2G4C (1 of 4) protein_coding Danio_rerio
ENSDARG00000042090 PLA2G4C (2 of 4) protein_coding Danio_rerio
ENSDARG00000045982 PLA2G4C (3 of 4) protein_coding Danio_rerio
ENSMUSG00000033847 Pla2g4c protein_coding Mus_musculus

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