ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: protein phosphatase 2, regulatory subunit A, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105568 PPP2R1A 9606 + 19:52190039-52229533 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000322088 PPP2R1A-001 52190039-52229533 protein_coding
  ENST00000391791 PPP2R1A-012 52220983-52226401 protein_coding
  ENST00000454220 PPP2R1A-004 52190051-52216602 protein_coding
  ENST00000462047 PPP2R1A-010 52212492-52215841 retained_intron
  ENST00000462990 PPP2R1A-003 52201093-52226417 protein_coding
  ENST00000468280 PPP2R1A-009 52190114-52211694 retained_intron
  ENST00000473455 PPP2R1A-008 52201767-52212698 processed_transcript
  ENST00000473820 PPP2R1A-011 52212830-52219734 retained_intron
  ENST00000477989 PPP2R1A-005 52190091-52191404 protein_coding
  ENST00000490868 PPP2R1A-006 52190048-52211483 nonsense_mediated_decay
  ENST00000495876 PPP2R1A-007 52201181-52211296 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000322088ENST00000391791ENST00000454220ENST00000462990ENST00000473820
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000322088 N/A N/A N/A N/A 11.826±10.99
ENST00000391791 247.580±30.76 95.956±37.76 107.890±0.00 75.157±0.00 62.176±27.53
ENST00000454220 N/A 9.731±0.00 N/A N/A 37.689±0.00
ENST00000462990 69.151±14.91 44.397±20.97 11.236±0.00 59.270±0.00 46.148±34.78
ENST00000473820 N/A 112.877±38.48 N/A N/A 63.925±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000159 TAS protein phosphatase type 2A complex
GO:0000184 TAS nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000188 NAS inactivation of MAPK activity
GO:0000278 TAS mitotic cell cycle
GO:0000775 IDA chromosome, centromeric region
GO:0003823 IPI antigen binding
GO:0004722 IEA protein serine/threonine phosphatase activity
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 NAS nucleus
GO:0005739 NAS mitochondrion
GO:0005829 TAS cytosol
GO:0006275 NAS regulation of DNA replication
GO:0006355 NAS regulation of transcription, DNA-templated
GO:0006461 TAS protein complex assembly
GO:0006470 TAS protein dephosphorylation
GO:0006672 NAS ceramide metabolic process
GO:0006915 TAS apoptotic process
GO:0007059 IDA chromosome segregation
GO:0007084 TAS mitotic nuclear envelope reassembly
GO:0008380 NAS RNA splicing
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0008601 TAS protein phosphatase type 2A regulator activity
GO:0010033 NAS response to organic substance
GO:0010467 TAS gene expression
GO:0015630 NAS microtubule cytoskeleton
GO:0016020 NAS membrane
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0019932 NAS second-messenger-mediated signaling
GO:0030111 NAS regulation of Wnt signaling pathway
GO:0030155 NAS regulation of cell adhesion
GO:0030308 NAS negative regulation of cell growth
GO:0040008 NAS regulation of growth
GO:0042518 NAS negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0045595 NAS regulation of cell differentiation
GO:0046982 IPI protein heterodimerization activity
GO:0070062 IDA extracellular vesicular exosome
GO:0070262 IEA peptidyl-serine dephosphorylation
GO:2001241 IEA positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000007564 Ppp2r1a protein_coding Mus_musculus

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