ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: phosphodiesterase 4C, cAMP-specific
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105650 PDE4C 9606 - 19:18207961-18255419 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262805 PDE4C-004 18210560-18226475 protein_coding
  ENST00000355502 PDE4C-001 18207961-18255419 protein_coding
  ENST00000447275 PDE4C-005 18210543-18224493 protein_coding
  ENST00000539010 PDE4C-201 18210831-18221161 protein_coding
  ENST00000593594 PDE4C-012 18220237-18221135 nonsense_mediated_decay
  ENST00000594465 PDE4C-003 18210560-18233671 protein_coding
  ENST00000594617 PDE4C-002 18208652-18248200 protein_coding
  ENST00000595343 PDE4C-013 18220237-18221135 nonsense_mediated_decay
  ENST00000596647 PDE4C-015 18249950-18255351 processed_transcript
  ENST00000597297 PDE4C-007 18210929-18221232 protein_coding
  ENST00000597360 PDE4C-006 18210552-18233385 retained_intron
  ENST00000597573 PDE4C-011 18220269-18221135 retained_intron
  ENST00000598111 PDE4C-008 18210929-18221122 protein_coding
  ENST00000599188 PDE4C-009 18210831-18226425 nonsense_mediated_decay
  ENST00000599754 PDE4C-010 18222286-18234256 protein_coding
  ENST00000600667 PDE4C-014 18250139-18252431 retained_intron
  ENST00000610023 PDE4C-016 18220905-18225786 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000262805ENST00000355502ENST00000447275ENST00000539010ENST00000593594ENST00000594617ENST00000597297ENST00000597360ENST00000598111ENST00000599188
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000262805 N/A 0.223±0.00 N/A N/A 0.114±0.03
ENST00000355502 0.027±0.00 0.216±0.04 N/A 0.045±0.00 0.040±0.02
ENST00000447275 N/A 0.011±0.00 N/A N/A 0.015±0.01
ENST00000539010 N/A N/A N/A N/A 0.116±0.07
ENST00000593594 N/A 0.090±0.00 N/A N/A N/A
ENST00000594617 0.137±0.12 0.098±0.07 0.274±0.00 N/A 0.077±0.07
ENST00000597297 N/A 0.323±0.00 N/A N/A 0.101±0.07
ENST00000597360 N/A 0.075±0.02 N/A 0.039±0.00 0.011±0.00
ENST00000598111 N/A 0.453±0.10 N/A N/A N/A
ENST00000599188 N/A N/A N/A N/A 0.064±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004114 IEA 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 TAS 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005615 IDA extracellular space
GO:0005829 TAS cytosol
GO:0006198 IEA cAMP catabolic process
GO:0007165 IEA signal transduction
GO:0008152 IEA metabolic process
GO:0046872 IEA metal ion binding
GO:0072372 ISS primary cilium

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002411 pde4cb protein_coding Danio_rerio
ENSDARG00000013221 pde4ca protein_coding Danio_rerio
ENSMUSG00000031842 Pde4c protein_coding Mus_musculus

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