ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: IMP (inosine 5'-monophosphate) dehydrogenase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106348 IMPDH1 9606 - 7:128392277-128410252 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000338791 IMPDH1-005 128392277-128410252 protein_coding
  ENST00000348127 IMPDH1-002 128392301-128409982 protein_coding
  ENST00000354269 IMPDH1-001 128392278-128409982 protein_coding
  ENST00000419067 IMPDH1-003 128392277-128409901 protein_coding
  ENST00000460045 IMPDH1-015 128394275-128395171 retained_intron
  ENST00000468842 IMPDH1-011 128398490-128400685 retained_intron
  ENST00000469328 IMPDH1-013 128392277-128405865 nonsense_mediated_decay
  ENST00000470772 IMPDH1-016 128392739-128405942 protein_coding
  ENST00000473463 IMPDH1-006 128400843-128409982 nonsense_mediated_decay
  ENST00000480861 IMPDH1-009 128392850-128405942 protein_coding
  ENST00000484496 IMPDH1-014 128392277-128409486 nonsense_mediated_decay
  ENST00000489263 IMPDH1-012 128400135-128409947 protein_coding
  ENST00000491376 IMPDH1-004 128400817-128409982 retained_intron
  ENST00000496200 IMPDH1-008 128392278-128405948 protein_coding
  ENST00000496487 IMPDH1-010 128400672-128405939 retained_intron
  ENST00000497868 IMPDH1-007 128398414-128409986 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000348127ENST00000354269ENST00000469328ENST00000470772ENST00000480861ENST00000496200ENST00000496487ENST00000497868
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000348127 N/A 5.732±1.46 N/A N/A 8.971±8.77
ENST00000354269 N/A N/A N/A N/A 8.773±7.93
ENST00000469328 12.573±0.00 N/A 2.772±0.00 N/A 2.936±0.47
ENST00000470772 N/A N/A N/A 7.265±0.00 9.285±2.86
ENST00000480861 N/A 3.742±0.00 N/A N/A 4.699±1.04
ENST00000496200 27.976±14.91 4.286±1.87 3.357±0.00 N/A 8.624±6.13
ENST00000496487 N/A N/A N/A N/A 1.271±0.10
ENST00000497868 N/A N/A N/A N/A 5.269±0.09

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001OE CIL_0001OE_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003676 IDA nucleic acid binding
GO:0003677 IDA DNA binding
GO:0003723 IEA RNA binding
GO:0003824 IEA catalytic activity
GO:0003938 IEA IMP dehydrogenase activity
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006144 TAS purine nucleobase metabolic process
GO:0006164 IEA purine nucleotide biosynthetic process
GO:0006177 IEA GMP biosynthetic process
GO:0009168 TAS purine ribonucleoside monophosphate biosynthetic process
GO:0016491 IEA oxidoreductase activity
GO:0018580 IEA nitronate monooxygenase activity
GO:0030554 IEA adenyl nucleotide binding
GO:0044281 TAS small molecule metabolic process
GO:0046651 IEA lymphocyte proliferation
GO:0046872 IEA metal ion binding
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029524 impdh1b protein_coding Danio_rerio
ENSDARG00000042336 impdh1a protein_coding Danio_rerio
ENSMUSG00000003500 Impdh1 protein_coding Mus_musculus

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