ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: nuclear respiratory factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106459 NRF1 9606 + 7:129611714-129757082 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000223190 NRF1-001 129611756-129756015 protein_coding
  ENST00000311967 NRF1-002 129611756-129756015 protein_coding
  ENST00000353868 NRF1-201 129630078-129757080 protein_coding
  ENST00000393230 NRF1-003 129630068-129757082 protein_coding
  ENST00000393232 NRF1-202 129611714-129757080 protein_coding
  ENST00000454688 NRF1-005 129611747-129709097 protein_coding
  ENST00000477428 NRF1-004 129611739-129633780 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000223190ENST00000311967ENST00000393230ENST00000393232ENST00000454688
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000223190 N/A 1.442±0.51 N/A 2.503±0.00 1.369±0.64
ENST00000311967 N/A N/A N/A N/A 0.504±0.00
ENST00000393230 2.366±1.15 0.532±0.00 N/A N/A 0.557±0.00
ENST00000393232 2.044±0.00 1.831±0.68 1.854±0.00 N/A 1.722±1.01
ENST00000454688 N/A N/A N/A N/A 2.521±0.30

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001YF CIL_0001YF_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001666 IEA response to hypoxia
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006091 TAS generation of precursor metabolites and energy
GO:0006351 IEA transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0007005 IEA mitochondrion organization
GO:0031100 IEA organ regeneration
GO:0032355 IEA response to estradiol
GO:0032496 IEA response to lipopolysaccharide
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0051593 IEA response to folic acid
GO:0051602 IEA response to electrical stimulus
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000018 nrf1 protein_coding Danio_rerio
ENSMUSG00000058440 Nrf1 protein_coding Mus_musculus

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