ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107679 PLEKHA1 9606 + 10:122374696-122442602 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000368988 PLEKHA1-201 122393105-122432354 protein_coding
  ENST00000368989 PLEKHA1-001 122374760-122432345 protein_coding
  ENST00000368990 PLEKHA1-002 122374696-122442602 protein_coding
  ENST00000392799 PLEKHA1-004 122386609-122430479 protein_coding
  ENST00000433307 PLEKHA1-202 122393128-122432354 protein_coding
  ENST00000463663 PLEKHA1-009 122374834-122412976 protein_coding
  ENST00000481451 PLEKHA1-006 122411771-122425731 retained_intron
  ENST00000494222 PLEKHA1-007 122374696-122416006 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000368988ENST00000368989ENST00000368990ENST00000392799ENST00000433307ENST00000481451
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000368988 1.809±0.00 2.236±0.80 N/A 3.160±0.00 3.640±1.85
ENST00000368989 N/A 4.299±1.73 1.070±0.00 12.966±0.00 13.776±11.79
ENST00000368990 N/A 1.056±0.00 N/A N/A 1.024±0.25
ENST00000392799 N/A N/A N/A N/A 3.879±1.36
ENST00000433307 2.685±0.26 3.359±0.98 4.833±0.00 4.042±0.00 5.853±3.64
ENST00000481451 N/A 2.001±0.06 N/A N/A 1.689±0.51

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001BB CIL_0001BB_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001553 IEA luteinization
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0007283 IEA spermatogenesis
GO:0008209 IEA androgen metabolic process
GO:0008210 IEA estrogen metabolic process
GO:0008585 IEA female gonad development
GO:0009791 IEA post-embryonic development
GO:0014065 IDA phosphatidylinositol 3-kinase signaling
GO:0030165 IPI PDZ domain binding
GO:0031529 IDA ruffle organization
GO:0032587 IDA ruffle membrane
GO:0033327 IEA Leydig cell differentiation
GO:0035264 IEA multicellular organism growth
GO:0043325 IDA phosphatidylinositol-3,4-bisphosphate binding
GO:0045184 IDA establishment of protein localization
GO:0048008 IEA platelet-derived growth factor receptor signaling pathway
GO:0048705 IEA skeletal system morphogenesis
GO:0050853 IDA B cell receptor signaling pathway
GO:0051898 IMP negative regulation of protein kinase B signaling
GO:0060021 IEA palate development
GO:0060325 IEA face morphogenesis
GO:0070062 IDA extracellular vesicular exosome
GO:0070301 IDA cellular response to hydrogen peroxide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030064 plekha1a protein_coding Danio_rerio
ENSDARG00000094504 plekha1b protein_coding Danio_rerio
ENSMUSG00000040268 Plekha1 protein_coding Mus_musculus

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