ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040268 Plekha1 10090 + 7:130865756-130913312 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000048180 Plekha1-003 130865910-130913302 protein_coding
  ENSMUST00000075181 Plekha1-001 130865898-130912068 protein_coding
  ENSMUST00000120441 Plekha1-002 130865756-130913312 protein_coding
  ENSMUST00000126355 Plekha1-011 130904904-130911163 protein_coding
  ENSMUST00000135359 Plekha1-012 130905304-130910901 retained_intron
  ENSMUST00000136963 Plekha1-009 130900534-130909676 processed_transcript
  ENSMUST00000140153 Plekha1-006 130865887-130878153 retained_intron
  ENSMUST00000146111 Plekha1-010 130902245-130908900 retained_intron
  ENSMUST00000148513 Plekha1-005 130865885-130894741 retained_intron
  ENSMUST00000149029 Plekha1-008 130896991-130905426 retained_intron
  ENSMUST00000151119 Plekha1-004 130865903-130909821 nonsense_mediated_decay
  ENSMUST00000154282 Plekha1-007 130882352-130885520 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECENSMUST00000048180ENSMUST00000075181ENSMUST00000120441ENSMUST00000148513
Transcript ID C166 Tie2+ EC
ENSMUST00000048180 2.393±0.40 6.079±2.82
ENSMUST00000075181 2.296±0.00 9.029±0.00
ENSMUST00000120441 4.127±1.30 9.540±7.65
ENSMUST00000148513 N/A 4.445±0.66

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002WI CIL_0002WI_0002 CGP
CIL_0001BE CIL_0001BE_0002 CGP
CIL_0001BB CIL_0001BB_0002 CGP
CIL_0005TA CIL_0005TA_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001553 IGI luteinization
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0007283 IMP spermatogenesis
GO:0008209 IMP androgen metabolic process
GO:0008210 IGI estrogen metabolic process
GO:0008585 IGI female gonad development
GO:0009791 IMP post-embryonic development
GO:0014065 IEA phosphatidylinositol 3-kinase signaling
GO:0030165 IEA PDZ domain binding
GO:0031529 IEA ruffle organization
GO:0032587 IEA ruffle membrane
GO:0033327 IMP Leydig cell differentiation
GO:0035264 IMP multicellular organism growth
GO:0043325 IEA phosphatidylinositol-3,4-bisphosphate binding
GO:0045184 IEA establishment of protein localization
GO:0048008 IMP platelet-derived growth factor receptor signaling pathway
GO:0048705 IMP skeletal system morphogenesis
GO:0050853 IEA B cell receptor signaling pathway
GO:0051898 IEA negative regulation of protein kinase B signaling
GO:0060021 IMP palate development
GO:0060325 IMP face morphogenesis
GO:0070062 IEA extracellular vesicular exosome
GO:0070301 IEA cellular response to hydrogen peroxide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030064 plekha1a protein_coding Danio_rerio
ENSDARG00000094504 plekha1b protein_coding Danio_rerio
ENSG00000107679 PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 protein_coding Homo_sapiens

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