ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: RAD51 paralog C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000108384 RAD51C 9606 + 17:58692573-58735611 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000337432 RAD51C-001 58692573-58735611 protein_coding
  ENST00000413590 RAD51C-011 58695148-58734229 protein_coding
  ENST00000421782 RAD51C-013 58692628-58695336 protein_coding
  ENST00000425173 RAD51C-006 58694990-58709876 protein_coding
  ENST00000461271 RAD51C-008 58692573-58709911 protein_coding
  ENST00000461706 RAD51C-012 58732332-58734331 retained_intron
  ENST00000475762 RAD51C-002 58692602-58734331 nonsense_mediated_decay
  ENST00000476741 RAD51C-005 58692602-58694880 processed_transcript
  ENST00000482007 RAD51C-003 58692615-58734327 nonsense_mediated_decay
  ENST00000486827 RAD51C-004 58692606-58695333 nonsense_mediated_decay
  ENST00000487525 RAD51C-007 58692606-58734325 nonsense_mediated_decay
  ENST00000487921 RAD51C-009 58692576-58705913 processed_transcript
  ENST00000578151 RAD51C-017 58709819-58734342 retained_intron
  ENST00000581221 RAD51C-015 58709639-58734327 retained_intron
  ENST00000583539 RAD51C-018 58692573-58732766 protein_coding
  ENST00000584617 RAD51C-014 58692663-58732519 nonsense_mediated_decay
  ENST00000584804 RAD51C-016 58709859-58734331 protein_coding
  ENST00000622327 RAD51C-019 58695050-58700253 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000337432ENST00000413590ENST00000421782ENST00000461271ENST00000461706ENST00000475762ENST00000476741ENST00000482007ENST00000486827ENST00000487525ENST00000487921ENST00000581221ENST00000583539ENST00000584617ENST00000584804
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000337432 1.027±0.00 0.855±0.19 0.726±0.00 N/A 0.860±0.34
ENST00000413590 5.892±0.00 4.188±0.00 N/A N/A 5.778±4.03
ENST00000421782 7.589±0.09 15.114±5.63 8.414±0.00 19.432±0.00 9.350±3.66
ENST00000461271 N/A 10.039±4.38 N/A N/A 5.986±2.06
ENST00000461706 N/A N/A 7.206±0.00 N/A N/A
ENST00000475762 N/A 0.763±0.00 N/A N/A 1.199±0.24
ENST00000476741 N/A N/A N/A N/A 0.196±0.00
ENST00000482007 6.263±0.00 8.109±4.12 N/A N/A 4.542±1.78
ENST00000486827 N/A N/A N/A N/A 0.502±0.09
ENST00000487525 N/A N/A N/A N/A 2.114±0.00
ENST00000487921 N/A 8.035±3.84 N/A 13.551±0.00 0.192±0.00
ENST00000581221 6.731±0.00 N/A 2.979±0.00 N/A N/A
ENST00000583539 N/A 2.814±0.18 N/A N/A 2.751±1.70
ENST00000584617 N/A 6.854±1.43 N/A N/A N/A
ENST00000584804 20.162±0.00 16.880±6.18 N/A N/A 7.284±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000566 CIL_000566_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000400 IDA four-way junction DNA binding
GO:0000724 IMP double-strand break repair via homologous recombination
GO:0000737 IEA DNA catabolic process, endonucleolytic
GO:0003677 IEA:TAS DNA binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005657 IDA replication fork
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0006200 IEA ATP catabolic process
GO:0006259 IEA DNA metabolic process
GO:0006281 IDA DNA repair
GO:0006310 IDA DNA recombination
GO:0007062 ISS sister chromatid cohesion
GO:0007066 IEA female meiosis sister chromatid cohesion
GO:0007131 IEA reciprocal meiotic recombination
GO:0007141 IEA male meiosis I
GO:0007283 IEA spermatogenesis
GO:0007596 TAS blood coagulation
GO:0008094 IEA DNA-dependent ATPase activity
GO:0008821 IMP crossover junction endodeoxyribonuclease activity
GO:0010971 IMP positive regulation of G2/M transition of mitotic cell cycle
GO:0033063 IDA Rad51B-Rad51C-Rad51D-XRCC2 complex
GO:0033065 IDA Rad51C-XRCC3 complex
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048476 IDA Holliday junction resolvase complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068919 rad51c protein_coding Danio_rerio
ENSMUSG00000007646 Rad51c protein_coding Mus_musculus

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