ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: septin 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000108387 SEPT4 9606 - 17:58520250-58540818 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000317256 SEPT4-006 58520359-58532046 protein_coding
  ENST00000317268 SEPT4-008 58520256-58529351 protein_coding
  ENST00000393086 SEPT4-201 58520250-58527144 protein_coding
  ENST00000412945 SEPT4-001 58520359-58540818 protein_coding
  ENST00000426861 SEPT4-004 58520255-58532050 protein_coding
  ENST00000457347 SEPT4-002 58520258-58540818 protein_coding
  ENST00000577440 SEPT4-005 58520256-58532050 retained_intron
  ENST00000577729 SEPT4-022 58521748-58532066 protein_coding
  ENST00000578131 SEPT4-021 58522051-58532065 nonsense_mediated_decay
  ENST00000578747 SEPT4-025 58526578-58531642 retained_intron
  ENST00000579371 SEPT4-013 58520256-58529279 protein_coding
  ENST00000580740 SEPT4-019 58526577-58532286 processed_transcript
  ENST00000580791 SEPT4-028 58526315-58527998 processed_transcript
  ENST00000580796 SEPT4-016 58520256-58528030 retained_intron
  ENST00000580809 SEPT4-003 58521549-58532054 protein_coding
  ENST00000580844 SEPT4-012 58520299-58529303 protein_coding
  ENST00000581607 SEPT4-024 58526765-58531941 protein_coding
  ENST00000581615 SEPT4-026 58522021-58529313 nonsense_mediated_decay
  ENST00000581921 SEPT4-018 58526223-58539158 processed_transcript
  ENST00000582248 SEPT4-027 58526563-58528013 retained_intron
  ENST00000582270 SEPT4-014 58520256-58529203 retained_intron
  ENST00000582976 SEPT4-029 58529818-58531524 retained_intron
  ENST00000583114 SEPT4-017 58520250-58527981 protein_coding
  ENST00000583273 SEPT4-010 58520256-58529350 retained_intron
  ENST00000583291 SEPT4-020 58525078-58532075 protein_coding
  ENST00000584488 SEPT4-011 58520426-58529313 retained_intron
  ENST00000584528 SEPT4-023 58526254-58532065 processed_transcript
  ENST00000584789 SEPT4-007 58525162-58532037 retained_intron
  ENST00000585170 SEPT4-015 58524588-58528569 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000317256ENST00000317268ENST00000393086ENST00000426861ENST00000577440ENST00000577729ENST00000578131ENST00000579371ENST00000580796ENST00000580809ENST00000580844ENST00000582270ENST00000582976ENST00000583114ENST00000583273ENST00000583291ENST00000584528ENST00000585170
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000317256 N/A 0.060±0.00 N/A N/A 0.779±0.27
ENST00000317268 N/A N/A N/A N/A 0.176±0.00
ENST00000393086 1.034±0.00 1.828±1.69 N/A N/A 1.044±0.91
ENST00000426861 N/A N/A 5.684±0.00 N/A 0.162±0.00
ENST00000577440 N/A N/A N/A 0.306±0.00 N/A
ENST00000577729 N/A N/A N/A N/A 0.224±0.08
ENST00000578131 N/A 0.463±0.00 N/A N/A N/A
ENST00000579371 N/A N/A N/A N/A 0.189±0.00
ENST00000580796 N/A N/A N/A 0.067±0.00 0.218±0.16
ENST00000580809 N/A N/A N/A N/A 0.141±0.04
ENST00000580844 0.962±0.00 0.153±0.00 N/A N/A 1.650±0.89
ENST00000582270 N/A N/A N/A N/A 0.054±0.00
ENST00000582976 N/A 0.079±0.03 N/A 0.091±0.00 0.245±0.13
ENST00000583114 N/A 0.187±0.00 N/A N/A N/A
ENST00000583273 N/A N/A N/A N/A 0.122±0.00
ENST00000583291 N/A N/A N/A N/A 2.664±2.36
ENST00000584528 N/A N/A N/A N/A 0.469±0.00
ENST00000585170 N/A N/A N/A N/A 0.071±0.05

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 TAS GTPase activity
GO:0005198 TAS structural molecule activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005634 NAS nucleus
GO:0005739 NAS mitochondrion
GO:0005856 IEA cytoskeleton
GO:0006184 TAS GTP catabolic process
GO:0006915 NAS apoptotic process
GO:0007049 IEA cell cycle
GO:0007286 IEA spermatid development
GO:0007420 IEA brain development
GO:0030382 IEA sperm mitochondrion organization
GO:0031105 IEA septin complex
GO:0031398 IDA positive regulation of protein ubiquitination
GO:0031514 IEA motile cilium
GO:0036126 IEA sperm flagellum
GO:0042981 NAS regulation of apoptotic process
GO:0042995 IEA cell projection
GO:0043065 IDA positive regulation of apoptotic process
GO:0048240 IEA sperm capacitation
GO:0051301 IEA cell division
GO:0097227 IEA sperm annulus
GO:2001244 IMP positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010385 sept4a protein_coding Danio_rerio
ENSMUSG00000020486 Sept4 protein_coding Mus_musculus

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