ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109062 SLC9A3R1 9606 + 17:74748652-74769353 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262613 SLC9A3R1-001 74748652-74769353 protein_coding
  ENST00000413388 SLC9A3R1-002 74762003-74769296 protein_coding
  ENST00000578958 SLC9A3R1-004 74763030-74768559 retained_intron
  ENST00000581356 SLC9A3R1-005 74763428-74768803 nonsense_mediated_decay
  ENST00000583369 SLC9A3R1-006 74748652-74768582 protein_coding

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000262613ENST00000413388ENST00000583369
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000262613 8.943±0.00 32.070±33.71 1.728±0.00 5.607±0.00 8.186±9.57
ENST00000413388 5.068±0.00 26.745±27.40 N/A N/A 3.857±2.79
ENST00000583369 N/A 1.618±0.00 N/A N/A 3.956±0.35

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000IB CIL_0000IB_0001 CGP
CIL_00032B CIL_00032B_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003096 IEA renal sodium ion transport
GO:0005102 IPI receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0005886 IDA plasma membrane
GO:0005902 IDA microvillus
GO:0006461 TAS protein complex assembly
GO:0007191 IEA adenylate cyclase-activating dopamine receptor signaling pathway
GO:0008013 IPI beta-catenin binding
GO:0008285 IDA negative regulation of cell proliferation
GO:0010642 ISS negative regulation of platelet-derived growth factor receptor signaling pathway
GO:0010766 IEA negative regulation of sodium ion transport
GO:0014067 ISS negative regulation of phosphatidylinositol 3-kinase signaling
GO:0015629 TAS actin cytoskeleton
GO:0016020 IDA membrane
GO:0016055 IEA Wnt signaling pathway
GO:0016324 IEA apical plasma membrane
GO:0017081 IDA chloride channel regulator activity
GO:0019902 IPI phosphatase binding
GO:0019904 IEA protein domain specific binding
GO:0030033 IMP microvillus assembly
GO:0030036 IEA actin cytoskeleton organization
GO:0030165 IPI PDZ domain binding
GO:0030336 IEA negative regulation of cell migration
GO:0030643 IEA cellular phosphate ion homeostasis
GO:0031526 IEA brush border membrane
GO:0031528 ISS microvillus membrane
GO:0031698 IPI beta-2 adrenergic receptor binding
GO:0031982 IDA vesicle
GO:0032403 IEA protein complex binding
GO:0032415 NAS regulation of sodium:proton antiporter activity
GO:0032416 IEA negative regulation of sodium:proton antiporter activity
GO:0032782 ISS bile acid secretion
GO:0032947 IEA protein complex scaffold
GO:0034613 IEA cellular protein localization
GO:0034635 ISS glutathione transport
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0043621 IDA protein self-association
GO:0044062 IEA regulation of excretion
GO:0045121 IEA membrane raft
GO:0045177 IEA apical part of cell
GO:0045859 ISS regulation of protein kinase activity
GO:0050780 IEA dopamine receptor binding
GO:0051898 IMP negative regulation of protein kinase B signaling
GO:0060158 IEA phospholipase C-activating dopamine receptor signaling pathway
GO:0070062 IDA extracellular vesicular exosome
GO:0070293 ISS renal absorption
GO:0070373 IDA negative regulation of ERK1 and ERK2 cascade
GO:0070851 IPI growth factor receptor binding
GO:0071944 IDA cell periphery
GO:0097225 ISS sperm midpiece
GO:0097291 IMP renal phosphate ion absorption
GO:2001244 IDA positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000068 slc9a3r1 protein_coding Danio_rerio
ENSMUSG00000020733 Slc9a3r1 protein_coding Mus_musculus

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