ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: chloride channel, voltage-sensitive 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109572 CLCN3 9606 + 4:169612633-169723673 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000347613 CLCN3-002 169620526-169720545 protein_coding
  ENST00000360642 CLCN3-004 169620529-169720278 protein_coding
  ENST00000502998 CLCN3-010 169680068-169680731 processed_transcript
  ENST00000504131 CLCN3-201 169662722-169723183 protein_coding
  ENST00000506924 CLCN3-008 169635983-169643168 processed_transcript
  ENST00000507875 CLCN3-005 169660062-169713187 protein_coding
  ENST00000511092 CLCN3-006 169612633-169689145 protein_coding
  ENST00000512813 CLCN3-007 169620552-169687755 protein_coding
  ENST00000513761 CLCN3-001 169620521-169723673 protein_coding
  ENST00000515420 CLCN3-009 169695631-169706888 protein_coding
  ENST00000613795 CLCN3-202 169660062-169723187 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000347613ENST00000360642ENST00000504131ENST00000507875ENST00000513761ENST00000613795
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000347613 N/A 8.051±3.72 7.637±0.00 8.047±5.37
ENST00000360642 N/A 4.435±2.01 N/A 4.999±1.61
ENST00000504131 2.035±0.79 7.305±3.49 10.837±0.00 7.256±4.11
ENST00000507875 N/A N/A N/A 2.520±1.79
ENST00000513761 N/A 2.496±0.00 2.933±0.00 2.701±1.92
ENST00000613795 N/A 2.223±0.32 N/A 2.784±1.82

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005216 IEA ion channel activity
GO:0005244 IEA voltage-gated ion channel activity
GO:0005247 IEA voltage-gated chloride channel activity
GO:0005254 TAS chloride channel activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005622 IEA intracellular
GO:0005769 IDA early endosome
GO:0005770 IDA late endosome
GO:0005794 IDA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0006810 TAS transport
GO:0006811 IEA ion transport
GO:0006821 IEA chloride transport
GO:0006885 TAS regulation of pH
GO:0009986 NAS cell surface
GO:0012506 IDA vesicle membrane
GO:0015297 IEA antiporter activity
GO:0016020 IDA:IEA membrane
GO:0016021 TAS integral component of membrane
GO:0016324 IEA apical plasma membrane
GO:0030165 IDA PDZ domain binding
GO:0030554 IEA adenyl nucleotide binding
GO:0031410 IEA cytoplasmic vesicle
GO:0034220 TAS ion transmembrane transport
GO:0034765 IEA regulation of ion transmembrane transport
GO:0042803 NAS protein homodimerization activity
GO:0044070 IEA regulation of anion transport
GO:0046982 IDA protein heterodimerization activity
GO:0048388 TAS endosomal lumen acidification
GO:0055085 TAS:IEA transmembrane transport
GO:1902476 TAS chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003269 clcn3 protein_coding Danio_rerio
ENSMUSG00000004319 Clcn3 protein_coding Mus_musculus

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