ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: RAD50 homolog (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113522 RAD50 9606 + 5:132556019-132646344 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000378823 RAD50-001 132556938-132646344 protein_coding
  ENST00000416135 RAD50-006 132556019-132579907 protein_coding
  ENST00000423956 RAD50-004 132557231-132609339 nonsense_mediated_decay
  ENST00000434288 RAD50-005 132591277-132593527 protein_coding
  ENST00000453394 RAD50-003 132557231-132595768 protein_coding
  ENST00000455677 RAD50-009 132618271-132643181 protein_coding
  ENST00000487596 RAD50-007 132579745-132588807 retained_intron
  ENST00000496204 RAD50-008 132595222-132603405 processed_transcript
  ENST00000533482 RAD50-002 132556938-132642476 nonsense_mediated_decay

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000378823ENST00000423956ENST00000453394ENST00000455677ENST00000533482
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000378823 N/A 1.072±0.56 2.640±0.00 1.439±0.67
ENST00000423956 N/A 0.796±0.08 2.057±0.00 1.694±0.34
ENST00000453394 N/A N/A N/A 3.038±0.37
ENST00000455677 9.649±4.40 N/A N/A N/A
ENST00000533482 N/A 1.933±1.09 4.605±0.00 2.251±2.10

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00093D CIL_00093D_0001 VISTA
CIL_0007RF CIL_0007RF_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000014 IDA single-stranded DNA endodeoxyribonuclease activity
GO:0000019 IDA regulation of mitotic recombination
GO:0000723 TAS:IEA telomere maintenance
GO:0000724 TAS double-strand break repair via homologous recombination
GO:0000737 IDA DNA catabolic process, endonucleolytic
GO:0000784 IDA nuclear chromosome, telomeric region
GO:0003677 IDA DNA binding
GO:0004003 IMP ATP-dependent DNA helicase activity
GO:0004518 IEA nuclease activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006281 IEA:IDA DNA repair
GO:0006302 IMP double-strand break repair
GO:0006310 IDA DNA recombination
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007004 IDA telomere maintenance via telomerase
GO:0007131 TAS reciprocal meiotic recombination
GO:0008270 IEA zinc ion binding
GO:0008408 IDA 3'-5' exonuclease activity
GO:0016020 IDA membrane
GO:0016887 IEA ATPase activity
GO:0030674 IDA protein binding, bridging
GO:0030870 IEA:IDA Mre11 complex
GO:0031954 IDA positive regulation of protein autophosphorylation
GO:0032508 IMP DNA duplex unwinding
GO:0033674 IDA positive regulation of kinase activity
GO:0035861 IDA site of double-strand break
GO:0045120 IEA pronucleus
GO:0090305 IDA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038917 rad50 protein_coding Danio_rerio
ENSMUSG00000020380 Rad50 protein_coding Mus_musculus

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