ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: RAD50 homolog (S. cerevisiae)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000378823 RAD50-001 ENSG00000113522 9606 + 5:132556938-132646344 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000378823
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000378823 1.072±0.56 2.640±0.00 1.439±0.67

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000014 IDA single-stranded DNA endodeoxyribonuclease activity
GO:0000019 IDA regulation of mitotic recombination
GO:0000723 TAS:IEA telomere maintenance
GO:0000724 TAS double-strand break repair via homologous recombination
GO:0000737 IDA DNA catabolic process, endonucleolytic
GO:0000784 IDA nuclear chromosome, telomeric region
GO:0003677 IDA DNA binding
GO:0004003 IMP ATP-dependent DNA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006281 IEA:IDA DNA repair
GO:0006302 IMP double-strand break repair
GO:0006310 IDA DNA recombination
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007004 IDA telomere maintenance via telomerase
GO:0007131 TAS reciprocal meiotic recombination
GO:0008270 IEA zinc ion binding
GO:0008408 IDA 3'-5' exonuclease activity
GO:0016020 IDA membrane
GO:0016887 IEA ATPase activity
GO:0030674 IDA protein binding, bridging
GO:0030870 IEA:IDA Mre11 complex
GO:0031954 IDA positive regulation of protein autophosphorylation
GO:0032508 IMP DNA duplex unwinding
GO:0033674 IDA positive regulation of kinase activity
GO:0035861 IDA site of double-strand break
GO:0045120 IEA pronucleus
GO:0090305 IDA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020649 Rad50-001 protein_coding Mus_musculus 0 4656
ENSMUST00000128483 Rad50-002 nonsense_mediated_decay Mus_musculus 0 1853
ENSMUST00000124352 Rad50-005 protein_coding Mus_musculus 0 1664
ENSMUST00000152598 Rad50-003 processed_transcript Mus_musculus 0 407
ENSMUST00000126121 Rad50-004 processed_transcript Mus_musculus 0 272
ENSMUST00000105321 Nfic-001 protein_coding Mus_musculus 0.000000002 71
ENSMUST00000091246 Flcn-005 protein_coding Mus_musculus 0.0000003 64
ENSMUST00000148151 Flcn-003 retained_intron Mus_musculus 0.0000003 64
ENSMUST00000102697 Flcn-004 protein_coding Mus_musculus 0.0000003 64
ENSMUST00000157025 Ctr9-003 retained_intron Mus_musculus 0.0005 53
ENSMUST00000152019 Ctr9-002 retained_intron Mus_musculus 0.0005 53

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