ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: epithelial cell transforming 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000114346 ECT2 9606 + 3:172750682-172821474 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000232458 ECT2-001 172750682-172821474 protein_coding
  ENST00000366090 ECT2-014 172750763-172757009 protein_coding
  ENST00000366254 ECT2-007 172750959-172754585 protein_coding
  ENST00000392692 ECT2-003 172750704-172821474 protein_coding
  ENST00000415665 ECT2-008 172750980-172759064 protein_coding
  ENST00000417960 ECT2-004 172750726-172821474 protein_coding
  ENST00000426894 ECT2-013 172750763-172757092 protein_coding
  ENST00000428567 ECT2-015 172750758-172761634 protein_coding
  ENST00000437296 ECT2-005 172802691-172821473 protein_coding
  ENST00000438041 ECT2-009 172751017-172757130 protein_coding
  ENST00000441497 ECT2-002 172754457-172820336 protein_coding
  ENST00000444250 ECT2-010 172762787-172783880 protein_coding
  ENST00000460860 ECT2-012 172802861-172806107 retained_intron
  ENST00000486027 ECT2-011 172807706-172820311 retained_intron
  ENST00000487073 ECT2-006 172818331-172820291 retained_intron
  ENST00000540509 ECT2-201 172750685-172821473 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000232458ENST00000392692ENST00000417960ENST00000437296ENST00000441497ENST00000540509
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000232458 0.573±0.00 2.101±2.02 N/A N/A 3.584±2.21
ENST00000392692 N/A 2.150±3.28 N/A 1.947±0.00 2.505±1.25
ENST00000417960 N/A N/A 0.311±0.00 N/A 1.810±0.16
ENST00000437296 0.954±0.00 1.045±0.00 0.862±0.00 N/A 0.624±0.00
ENST00000441497 N/A 1.697±0.87 N/A 5.308±0.00 3.105±1.06
ENST00000540509 N/A 2.649±0.00 N/A N/A 1.391±0.48

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IEA cell morphogenesis
GO:0000910 IEA:IMP cytokinesis
GO:0004871 IMP signal transducer activity
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 IDA:IEA Rho guanyl-nucleotide exchange factor activity
GO:0005096 IEA:IMP GTPase activator activity
GO:0005515 IPI protein binding
GO:0005634 IEA:IDA nucleus
GO:0005737 IEA:IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005911 IDA cell-cell junction
GO:0005923 IDA tight junction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0015031 IEA protein transport
GO:0017048 IEA Rho GTPase binding
GO:0030496 IDA midbody
GO:0032147 IDA activation of protein kinase activity
GO:0032154 IDA cleavage furrow
GO:0032321 IDA positive regulation of Rho GTPase activity
GO:0032467 IMP positive regulation of cytokinesis
GO:0032862 IDA activation of Rho GTPase activity
GO:0032863 IMP activation of Rac GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0042307 ISS positive regulation of protein import into nucleus
GO:0042803 IDA protein homodimerization activity
GO:0043065 IDA positive regulation of apoptotic process
GO:0043089 IDA positive regulation of Cdc42 GTPase activity
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043547 IEA positive regulation of GTPase activity
GO:0045666 IEA:ISS positive regulation of neuron differentiation
GO:0045859 IDA regulation of protein kinase activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0051260 IDA protein homooligomerization
GO:0051988 IMP regulation of attachment of spindle microtubules to kinetochore
GO:0070301 IDA cellular response to hydrogen peroxide
GO:0070830 IMP tight junction assembly
GO:0071277 IDA cellular response to calcium ion
GO:0071479 IDA cellular response to ionizing radiation
GO:0072686 IDA mitotic spindle
GO:0097149 IDA centralspindlin complex
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007278 ect2 protein_coding Danio_rerio
ENSMUSG00000027699 Ect2 protein_coding Mus_musculus

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