ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027699 Ect2 10090 - 3:27097222-27153878 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000108296 Ect2-004 27121878-27153812 retained_intron
  ENSMUST00000108298 Ect2-001 27097222-27153878 protein_coding
  ENSMUST00000108300 Ect2-002 27097222-27153861 protein_coding
  ENSMUST00000124727 Ect2-005 27131463-27137136 retained_intron
  ENSMUST00000150061 Ect2-006 27098306-27117807 nonsense_mediated_decay
  ENSMUST00000175857 Ect2-010 27146028-27153782 protein_coding
  ENSMUST00000176242 Ect2-201 27097223-27153854 protein_coding
  ENSMUST00000176535 Ect2-008 27145968-27153828 protein_coding
  ENSMUST00000176780 Ect2-007 27145020-27153854 protein_coding
  ENSMUST00000176908 Ect2-011 27117852-27122692 retained_intron
  ENSMUST00000177055 Ect2-009 27145984-27153810 protein_coding
  ENSMUST00000184113 Ect2-003 27097226-27153850 nonsense_mediated_decay
  ENSMUST00000196926 Ect2-012 27144950-27147201 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000108296ENSMUST00000108298ENSMUST00000108300ENSMUST00000176242ENSMUST00000176535ENSMUST00000184113
Transcript ID C166 Tie2+ EC mES
ENSMUST00000108296 N/A 2.331±1.92 N/A
ENSMUST00000108298 9.562±1.41 1.671±0.22 N/A
ENSMUST00000108300 9.168±5.37 1.104±0.00 3.816±0.00
ENSMUST00000176242 6.081±1.52 0.762±0.34 2.589±0.00
ENSMUST00000176535 N/A 9.030±0.00 N/A
ENSMUST00000184113 N/A 1.015±0.86 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IDA cell morphogenesis
GO:0000910 IEA:ISS cytokinesis
GO:0004871 IEA signal transducer activity
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 ISS Rho guanyl-nucleotide exchange factor activity
GO:0005096 IEA:ISS GTPase activator activity
GO:0005515 IPI protein binding
GO:0005634 IEA:IDA nucleus
GO:0005737 IEA:IDA cytoplasm
GO:0005911 ISS cell-cell junction
GO:0005923 ISS tight junction
GO:0015031 IEA protein transport
GO:0017048 IPI Rho GTPase binding
GO:0030496 ISS midbody
GO:0032147 ISS activation of protein kinase activity
GO:0032154 ISS cleavage furrow
GO:0032321 ISS positive regulation of Rho GTPase activity
GO:0032467 ISS positive regulation of cytokinesis
GO:0032862 ISS activation of Rho GTPase activity
GO:0032863 ISS activation of Rac GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0042307 IDA positive regulation of protein import into nucleus
GO:0042803 ISS protein homodimerization activity
GO:0043065 ISS positive regulation of apoptotic process
GO:0043089 ISS positive regulation of Cdc42 GTPase activity
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043547 IEA positive regulation of GTPase activity
GO:0045666 IEA:IMP positive regulation of neuron differentiation
GO:0045859 ISS regulation of protein kinase activity
GO:0051260 ISS protein homooligomerization
GO:0051988 ISS regulation of attachment of spindle microtubules to kinetochore
GO:0070301 ISS cellular response to hydrogen peroxide
GO:0070830 ISS tight junction assembly
GO:0071277 ISS cellular response to calcium ion
GO:0071479 ISS cellular response to ionizing radiation
GO:0072686 ISS mitotic spindle
GO:0097149 ISS centralspindlin complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007278 ect2 protein_coding Danio_rerio
ENSG00000114346 ECT2 epithelial cell transforming 2 protein_coding Homo_sapiens

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