ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000114353 GNAI2 9606 + 3:50226292-50259355 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000266027 GNAI2-201 50230776-50259339 protein_coding
  ENST00000313601 GNAI2-001 50235952-50259355 protein_coding
  ENST00000422163 GNAI2-003 50226292-50258898 protein_coding
  ENST00000440628 GNAI2-009 50238112-50258751 protein_coding
  ENST00000441156 GNAI2-005 50236204-50259354 nonsense_mediated_decay
  ENST00000446079 GNAI2-004 50226737-50258898 nonsense_mediated_decay
  ENST00000451956 GNAI2-002 50246894-50258697 protein_coding
  ENST00000468422 GNAI2-010 50253154-50256691 retained_intron
  ENST00000480090 GNAI2-008 50230810-50235290 processed_transcript
  ENST00000490122 GNAI2-006 50251409-50258893 retained_intron
  ENST00000491100 GNAI2-007 50229065-50259345 processed_transcript
  ENST00000492383 GNAI2-011 50256283-50258166 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000266027ENST00000313601ENST00000440628ENST00000441156ENST00000451956
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000266027 327.665±0.00 N/A N/A N/A 53.882±14.84
ENST00000313601 71.006±8.97 243.270±92.81 N/A 227.642±0.00 283.235±242.07
ENST00000440628 N/A N/A N/A N/A 1.423±0.00
ENST00000441156 179.515±74.59 194.084±85.32 160.655±0.00 125.773±0.00 143.949±39.30
ENST00000451956 N/A 308.560±156.98 N/A 98.632±0.00 251.888±284.89

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000186 IEA activation of MAPKK activity
GO:0001664 IBA G-protein coupled receptor binding
GO:0001973 IBA adenosine receptor signaling pathway
GO:0003924 IBA:IEA GTPase activity
GO:0004871 IBA:IEA signal transducer activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0005829 IEA cytosol
GO:0005834 IBA heterotrimeric G-protein complex
GO:0005886 IDA plasma membrane
GO:0006184 IEA GTP catabolic process
GO:0007049 IEA cell cycle
GO:0007165 TAS:IEA signal transduction
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007193 IBA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007194 TAS negative regulation of adenylate cyclase activity
GO:0007213 IEA G-protein coupled acetylcholine receptor signaling pathway
GO:0007214 IBA gamma-aminobutyric acid signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007584 TAS response to nutrient
GO:0007596 TAS blood coagulation
GO:0008283 IEA cell proliferation
GO:0008284 IEA positive regulation of cell proliferation
GO:0016020 IDA membrane
GO:0019001 IEA guanyl nucleotide binding
GO:0030168 TAS platelet activation
GO:0030496 IDA midbody
GO:0031683 IBA:IEA G-protein beta/gamma-subunit complex binding
GO:0031982 IDA vesicle
GO:0035556 IEA intracellular signal transduction
GO:0045121 IEA membrane raft
GO:0046872 IEA metal ion binding
GO:0050805 IEA negative regulation of synaptic transmission
GO:0051301 IMP cell division
GO:0051924 IEA regulation of calcium ion transport
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017294 gnai2b protein_coding Danio_rerio
ENSDARG00000018174 gnai2a protein_coding Danio_rerio
ENSMUSG00000032562 Gnai2 protein_coding Mus_musculus

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