ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000313601 GNAI2-001 ENSG00000114353 9606 + 3:50235952-50259355 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000313601
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000313601 71.006±8.97 243.270±92.81 227.642±0.00 283.235±242.07

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000186 IEA activation of MAPKK activity
GO:0001664 IBA G-protein coupled receptor binding
GO:0001973 IBA adenosine receptor signaling pathway
GO:0003924 IBA:IEA GTPase activity
GO:0004871 IBA:IEA signal transducer activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0005829 IEA cytosol
GO:0005834 IBA heterotrimeric G-protein complex
GO:0005886 IDA plasma membrane
GO:0006184 IEA GTP catabolic process
GO:0007049 IEA cell cycle
GO:0007165 TAS:IEA signal transduction
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007193 IBA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007194 TAS negative regulation of adenylate cyclase activity
GO:0007213 IEA G-protein coupled acetylcholine receptor signaling pathway
GO:0007214 IBA gamma-aminobutyric acid signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007584 TAS response to nutrient
GO:0007596 TAS blood coagulation
GO:0008283 IEA cell proliferation
GO:0008284 IEA positive regulation of cell proliferation
GO:0016020 IDA membrane
GO:0019001 IEA guanyl nucleotide binding
GO:0030168 TAS platelet activation
GO:0030496 IDA midbody
GO:0031683 IBA:IEA G-protein beta/gamma-subunit complex binding
GO:0031982 IDA vesicle
GO:0035556 IEA intracellular signal transduction
GO:0045121 IEA membrane raft
GO:0046872 IEA metal ion binding
GO:0050805 IEA negative regulation of synaptic transmission
GO:0051301 IMP cell division
GO:0051924 IEA regulation of calcium ion transport
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000055704 Gnai2-001 protein_coding Mus_musculus 0 2606
ENSMUST00000192615 Gnai2-003 protein_coding Mus_musculus 0 1640
ENSDART00000128070 gnai2a-001 protein_coding Danio_rerio 0 784
ENSMUST00000193835 Gnai2-007 retained_intron Mus_musculus 0 752
ENSMUST00000074694 Gnai1-001 protein_coding Mus_musculus 0 702
ENSMUST00000193394 Gnai2-008 protein_coding Mus_musculus 0 665
ENSDART00000047528 gnai3-001 protein_coding Danio_rerio 0 645
ENSMUST00000193372 Gnai2-004 retained_intron Mus_musculus 0 512
ENSMUST00000193538 Gnai2-009 retained_intron Mus_musculus 0 453
ENSMUST00000159991 Gnaz-002 protein_coding Mus_musculus 0 392
ENSMUST00000037813 Gnaz-001 protein_coding Mus_musculus 0 392
ENSMUST00000195231 Gnai2-005 retained_intron Mus_musculus 0 370
ENSMUST00000192837 Gnai2-010 protein_coding Mus_musculus 0 350
ENSMUST00000138659 Gnao1-003 processed_transcript Mus_musculus 0 324
ENSMUST00000195762 Gnai2-006 retained_intron Mus_musculus 0 244
ENSMUST00000193876 Gnai2-012 protein_coding Mus_musculus 0 226
ENSMUST00000144451 Gnao1-009 processed_transcript Mus_musculus 9.99995e-41 172
ENSMUST00000160421 Gnaz-003 processed_transcript Mus_musculus 4e-35 154

Loading