ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: reticulon 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115310 RTN4 9606 - 2:54972187-55112621 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000317610 RTN4-002 54972189-55050544 protein_coding
  ENST00000337526 RTN4-001 54972189-55050544 protein_coding
  ENST00000357376 RTN4-014 54972189-55049198 protein_coding
  ENST00000357732 RTN4-007 54972189-55050544 protein_coding
  ENST00000394609 RTN4-008 54972187-55010449 protein_coding
  ENST00000394611 RTN4-013 54972189-55050598 protein_coding
  ENST00000402434 RTN4-201 54972814-55050376 protein_coding
  ENST00000404909 RTN4-006 54972189-55050828 protein_coding
  ENST00000405240 RTN4-003 54972189-55046886 protein_coding
  ENST00000427710 RTN4-004 55027207-55112621 protein_coding
  ENST00000438462 RTN4-012 54973513-55049640 protein_coding
  ENST00000461004 RTN4-005 55056483-55112567 processed_transcript
  ENST00000485749 RTN4-011 54972797-54974191 processed_transcript
  ENST00000486085 RTN4-009 54972585-54987633 processed_transcript
  ENST00000491592 RTN4-010 54972796-54974019 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000317610ENST00000394609ENST00000402434ENST00000438462ENST00000486085
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000317610 61.788±48.17 136.427±50.78 7.426±0.00 336.527±0.00 277.152±333.73
ENST00000394609 N/A N/A N/A N/A 22.539±2.64
ENST00000402434 N/A N/A N/A N/A 45.305±0.00
ENST00000438462 N/A N/A N/A N/A 78.327±15.79
ENST00000486085 N/A N/A N/A N/A 45.604±7.91

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0005515 IPI protein binding
GO:0005622 IMP intracellular
GO:0005635 IDA nuclear envelope
GO:0005783 IDA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0006915 NAS apoptotic process
GO:0007399 IEA nervous system development
GO:0007413 ISS axonal fasciculation
GO:0016021 IEA integral component of membrane
GO:0021801 ISS cerebral cortex radial glia guided migration
GO:0030176 IDA integral component of endoplasmic reticulum membrane
GO:0030308 IMP negative regulation of cell growth
GO:0030334 IDA regulation of cell migration
GO:0030517 IDA negative regulation of axon extension
GO:0042981 NAS regulation of apoptotic process
GO:0042995 IEA cell projection
GO:0043025 IEA neuronal cell body
GO:0044822 IDA poly(A) RNA binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050770 TAS regulation of axonogenesis
GO:0050771 TAS negative regulation of axonogenesis
GO:0051960 IEA regulation of nervous system development
GO:0060317 IEA cardiac epithelial to mesenchymal transition
GO:0070062 IDA extracellular vesicular exosome
GO:0071786 IMP endoplasmic reticulum tubular network organization
GO:2000172 ISS regulation of branching morphogenesis of a nerve

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044601 rtn4a protein_coding Danio_rerio
ENSMUSG00000020458 Rtn4 protein_coding Mus_musculus

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