ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: insulin-like growth factor binding protein 2, 36kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115457 IGFBP2 9606 + 2:216632828-216664436 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000233809 IGFBP2-001 216633395-216664436 protein_coding
  ENST00000434997 IGFBP2-003 216632828-216661917 protein_coding
  ENST00000436812 IGFBP2-005 216660733-216664409 protein_coding
  ENST00000456764 IGFBP2-004 216659618-216664285 protein_coding
  ENST00000490362 IGFBP2-002 216633429-216664433 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000233809ENST00000436812ENST00000456764ENST00000490362
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000233809 8.477±0.00 30.189±13.43 5.371±0.00 2.323±0.00 74.844±61.66
ENST00000436812 N/A N/A 7.576±0.00 N/A 17.869±2.05
ENST00000456764 8.736±2.24 32.258±21.02 5.807±0.00 N/A 56.408±45.33
ENST00000490362 N/A N/A N/A N/A 0.136±0.09

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005MF CIL_0005MF_0001 CGP
CIL_0000AM CIL_0000AM_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 IEA regulation of cell growth
GO:0005515 IPI protein binding
GO:0005520 IEA insulin-like growth factor binding
GO:0005576 ISS:IEA extracellular region
GO:0005615 IDA extracellular space
GO:0007165 IEA signal transduction
GO:0007565 IEA female pregnancy
GO:0007568 IEA aging
GO:0007584 IEA response to nutrient
GO:0009612 IEA response to mechanical stimulus
GO:0010226 IEA response to lithium ion
GO:0016324 IEA apical plasma membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0031994 IDA insulin-like growth factor I binding
GO:0031995 ISS insulin-like growth factor II binding
GO:0032355 IEA response to estradiol
GO:0032526 IEA response to retinoic acid
GO:0032870 IEA cellular response to hormone stimulus
GO:0042104 IDA positive regulation of activated T cell proliferation
GO:0042493 IEA response to drug
GO:0043567 ISS regulation of insulin-like growth factor receptor signaling pathway
GO:0043627 IEA response to estrogen
GO:0044267 TAS cellular protein metabolic process
GO:0048545 IEA response to steroid hormone
GO:0051384 IEA response to glucocorticoid
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031422 igfbp2b protein_coding Danio_rerio
ENSDARG00000052470 igfbp2a protein_coding Danio_rerio
ENSMUSG00000039323 Igfbp2 protein_coding Mus_musculus

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