ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039323 Igfbp2 10090 + 1:72824503-72852474 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000047328 Igfbp2-001 72824503-72852474 protein_coding
  ENSMUST00000120564 Igfbp2-002 72825322-72852467 protein_coding
  ENSMUST00000155703 Igfbp2-003 72848699-72852148 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000047328ENSMUST00000120564
Transcript ID C166 Tie2+ EC mES
ENSMUST00000047328 0.258±0.13 4.746±3.00 88.846±18.68
ENSMUST00000120564 0.099±0.02 4.736±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005MF CIL_0005MF_0002 CGP
CIL_0000AM CIL_0000AM_0003 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 IEA regulation of cell growth
GO:0005515 IEA protein binding
GO:0005520 IPI insulin-like growth factor binding
GO:0005576 ISS extracellular region
GO:0005615 IDA extracellular space
GO:0007165 IEA signal transduction
GO:0007565 IEA female pregnancy
GO:0007568 IEA aging
GO:0007584 IEA response to nutrient
GO:0009612 IEA response to mechanical stimulus
GO:0010226 IEA response to lithium ion
GO:0016324 IEA apical plasma membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0031994 ISS insulin-like growth factor I binding
GO:0031995 ISS insulin-like growth factor II binding
GO:0032355 IEA response to estradiol
GO:0032526 IEA response to retinoic acid
GO:0032870 IEA cellular response to hormone stimulus
GO:0042104 ISS positive regulation of activated T cell proliferation
GO:0042493 IEA response to drug
GO:0043567 ISS regulation of insulin-like growth factor receptor signaling pathway
GO:0043627 IEA response to estrogen
GO:0048545 IEA response to steroid hormone
GO:0051384 IEA response to glucocorticoid
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031422 igfbp2b protein_coding Danio_rerio
ENSDARG00000052470 igfbp2a protein_coding Danio_rerio
ENSG00000115457 IGFBP2 insulin-like growth factor binding protein 2, 36kDa protein_coding Homo_sapiens

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