ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: 3-ketodihydrosphingosine reductase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000119537 KDSR 9606 - 18:63327726-63367510 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000326575 KDSR-010 63331651-63367204 protein_coding
  ENST00000406396 KDSR-001 63327726-63367510 protein_coding
  ENST00000585456 KDSR-006 63359525-63367128 retained_intron
  ENST00000585750 KDSR-007 63344342-63355514 retained_intron
  ENST00000586791 KDSR-002 63330825-63346530 retained_intron
  ENST00000587292 KDSR-005 63362843-63367206 processed_transcript
  ENST00000588089 KDSR-011 63331404-63336023 retained_intron
  ENST00000589530 KDSR-008 63355316-63367203 retained_intron
  ENST00000589592 KDSR-012 63331643-63346616 processed_transcript
  ENST00000590056 KDSR-004 63366431-63367228 processed_transcript
  ENST00000591902 KDSR-009 63331383-63355533 protein_coding
  ENST00000592327 KDSR-013 63351015-63367204 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000326575ENST00000406396ENST00000586791ENST00000591902ENST00000592327
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000326575 N/A 8.181±1.78 N/A 2.574±2.15
ENST00000406396 0.942±0.00 1.713±0.61 4.232±0.00 3.765±2.86
ENST00000586791 N/A N/A N/A 0.682±0.20
ENST00000591902 N/A 15.139±2.58 11.694±0.00 9.834±7.12
ENST00000592327 N/A 18.799±4.35 N/A 0.775±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000B4 CIL_0000B4_0002 CGP
CIL_0000B7 CIL_0000B7_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005615 TAS extracellular space
GO:0005783 IDA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006665 TAS sphingolipid metabolic process
GO:0006666 IDA 3-keto-sphinganine metabolic process
GO:0008152 IEA metabolic process
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016491 IEA oxidoreductase activity
GO:0030148 TAS sphingolipid biosynthetic process
GO:0044281 TAS small molecule metabolic process
GO:0047560 IDA 3-dehydrosphinganine reductase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012021 kdsr protein_coding Danio_rerio
ENSMUSG00000009905 Kdsr protein_coding Mus_musculus

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