ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: FK506 binding protein 1B, 12.6 kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000119782 FKBP1B 9606 + 2:24049701-24063681 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000380986 FKBP1B-001 24049714-24063681 protein_coding
  ENST00000380991 FKBP1B-002 24049701-24063681 protein_coding
  ENST00000421839 FKBP1B-004 24053911-24063681 nonsense_mediated_decay
  ENST00000438630 FKBP1B-003 24049731-24063681 nonsense_mediated_decay
  ENST00000452109 FKBP1B-006 24049771-24063671 protein_coding
  ENST00000496149 FKBP1B-005 24049752-24063656 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000380986ENST00000380991ENST00000421839ENST00000438630ENST00000452109ENST00000496149
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000380986 10.085±0.06 6.670±3.04 N/A 2.382±0.00 4.753±2.59
ENST00000380991 N/A 5.978±2.87 N/A 6.111±0.00 4.982±2.35
ENST00000421839 10.789±6.74 7.315±2.99 3.106±0.00 N/A 4.689±3.83
ENST00000438630 N/A 0.322±0.00 N/A N/A 2.511±0.00
ENST00000452109 N/A N/A 0.823±0.00 1.725±0.00 N/A
ENST00000496149 N/A N/A N/A N/A 0.271±0.18

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000413 IEA:IDA protein peptidyl-prolyl isomerization
GO:0002027 IEA regulation of heart rate
GO:0003755 IDA peptidyl-prolyl cis-trans isomerase activity
GO:0005102 IPI receptor binding
GO:0005219 TAS ryanodine-sensitive calcium-release channel activity
GO:0005515 IPI protein binding
GO:0005528 IDA FK506 binding
GO:0005737 IDA cytoplasm
GO:0005829 IC cytosol
GO:0006457 IEA protein folding
GO:0006458 TAS 'de novo' protein folding
GO:0006939 IEA smooth muscle contraction
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0009749 IEA response to glucose
GO:0010033 IEA response to organic substance
GO:0010459 ISS negative regulation of heart rate
GO:0010880 IDA regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881 ISS regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0014808 IEA release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0016020 IDA membrane
GO:0016529 IEA sarcoplasmic reticulum
GO:0019227 IEA neuronal action potential propagation
GO:0019855 IDA calcium channel inhibitor activity
GO:0022417 TAS protein maturation by protein folding
GO:0030018 IDA Z disc
GO:0030073 IEA insulin secretion
GO:0030551 IEA cyclic nucleotide binding
GO:0032513 IDA negative regulation of protein phosphatase type 2B activity
GO:0033017 IBA sarcoplasmic reticulum membrane
GO:0033197 IEA response to vitamin E
GO:0034704 IDA calcium channel complex
GO:0035584 TAS calcium-mediated signaling using intracellular calcium source
GO:0042026 TAS protein refolding
GO:0042098 IEA T cell proliferation
GO:0042542 IEA response to hydrogen peroxide
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044325 ISS ion channel binding
GO:0048680 IEA positive regulation of axon regeneration
GO:0051209 IEA release of sequestered calcium ion into cytosol
GO:0051280 IDA negative regulation of release of sequestered calcium ion into cytosol
GO:0051284 IDA positive regulation of sequestering of calcium ion
GO:0051480 IDA cytosolic calcium ion homeostasis
GO:0051775 IDA response to redox state
GO:0060314 IDA regulation of ryanodine-sensitive calcium-release channel activity
GO:0060315 IDA negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0061077 IBA chaperone-mediated protein folding
GO:0061179 IEA negative regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0070588 TAS calcium ion transmembrane transport
GO:0086064 TAS cell communication by electrical coupling involved in cardiac conduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052625 fkbp1b protein_coding Danio_rerio
ENSMUSG00000020635 Fkbp1b protein_coding Mus_musculus

Loading