ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020635 Fkbp1b 10090 - 12:4833175-4841595 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020964 Fkbp1b-201 4833175-4841595 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000020964
Transcript ID C166 Tie2+ EC mES
ENSMUST00000020964 2.412±0.73 1.123±0.40 5.534±3.68

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003JZ CIL_0003JZ_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000413 IEA protein peptidyl-prolyl isomerization
GO:0002027 IMP regulation of heart rate
GO:0003755 IDA peptidyl-prolyl cis-trans isomerase activity
GO:0005102 IEA receptor binding
GO:0005515 IPI protein binding
GO:0005528 IDA FK506 binding
GO:0005737 IEA cytoplasm
GO:0006939 IMP smooth muscle contraction
GO:0007204 IMP positive regulation of cytosolic calcium ion concentration
GO:0009749 IMP response to glucose
GO:0010033 IEA response to organic substance
GO:0010459 IMP negative regulation of heart rate
GO:0010880 IMP regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881 IMP regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0014808 IMP release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0016020 IEA membrane
GO:0016529 IDA sarcoplasmic reticulum
GO:0019227 IMP neuronal action potential propagation
GO:0019855 IBA calcium channel inhibitor activity
GO:0030018 IEA Z disc
GO:0030073 IMP insulin secretion
GO:0030551 IEA cyclic nucleotide binding
GO:0032513 IEA negative regulation of protein phosphatase type 2B activity
GO:0033017 IDA sarcoplasmic reticulum membrane
GO:0033197 IEA response to vitamin E
GO:0034704 IDA calcium channel complex
GO:0042098 IMP T cell proliferation
GO:0042542 IEA response to hydrogen peroxide
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044325 IPI ion channel binding
GO:0048680 IEA positive regulation of axon regeneration
GO:0051209 IMP release of sequestered calcium ion into cytosol
GO:0051280 IBA negative regulation of release of sequestered calcium ion into cytosol
GO:0051284 IEA positive regulation of sequestering of calcium ion
GO:0051480 IMP cytosolic calcium ion homeostasis
GO:0051775 IEA response to redox state
GO:0060314 IMP regulation of ryanodine-sensitive calcium-release channel activity
GO:0060315 IEA negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0061077 IBA chaperone-mediated protein folding
GO:0061179 IMP negative regulation of insulin secretion involved in cellular response to glucose stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052625 fkbp1b protein_coding Danio_rerio
ENSG00000119782 FKBP1B FK506 binding protein 1B, 12.6 kDa protein_coding Homo_sapiens

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