ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: TAR DNA binding protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000120948 TARDBP 9606 + 1:11012344-11026420 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000240185 TARDBP-001 11012400-11026420 protein_coding
  ENST00000315091 TARDBP-003 11013716-11024183 protein_coding
  ENST00000439080 TARDBP-011 11012653-11022858 nonsense_mediated_decay
  ENST00000472476 TARDBP-006 11012654-11022176 nonsense_mediated_decay
  ENST00000473118 TARDBP-004 11012344-11020489 protein_coding
  ENST00000473869 TARDBP-002 11013716-11025019 nonsense_mediated_decay
  ENST00000476201 TARDBP-005 11012654-11020589 protein_coding
  ENST00000477447 TARDBP-007 11020587-11025207 nonsense_mediated_decay
  ENST00000480464 TARDBP-009 11023929-11025492 processed_transcript
  ENST00000496840 TARDBP-008 11023198-11025739 nonsense_mediated_decay
  ENST00000610369 TARDBP-022 11018853-11024043 protein_coding
  ENST00000611008 TARDBP-026 11022818-11025492 processed_transcript
  ENST00000611963 TARDBP-020 11016966-11024193 nonsense_mediated_decay
  ENST00000613177 TARDBP-027 11023045-11025203 processed_transcript
  ENST00000613864 TARDBP-014 11012654-11018453 processed_transcript
  ENST00000614494 TARDBP-023 11020433-11024183 nonsense_mediated_decay
  ENST00000616545 TARDBP-013 11013728-11023341 protein_coding
  ENST00000617172 TARDBP-019 11016865-11023590 protein_coding
  ENST00000617757 TARDBP-028 11023323-11024152 processed_transcript
  ENST00000618606 TARDBP-015 11016878-11019186 retained_intron
  ENST00000619555 TARDBP-018 11018780-11024184 nonsense_mediated_decay
  ENST00000620505 TARDBP-024 11022308-11025221 nonsense_mediated_decay
  ENST00000620632 TARDBP-021 11018780-11024043 nonsense_mediated_decay
  ENST00000621573 TARDBP-025 11022548-11024273 nonsense_mediated_decay
  ENST00000621715 TARDBP-016 11012670-11022310 protein_coding
  ENST00000621790 TARDBP-012 11013728-11023341 protein_coding
  ENST00000622057 TARDBP-017 11016859-11023287 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000240185ENST00000315091ENST00000439080ENST00000610369ENST00000613864ENST00000617757ENST00000621573
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000240185 N/A 3.073±0.01 N/A N/A 5.828±4.94
ENST00000315091 46.900±4.02 37.597±14.64 58.181±0.00 44.996±0.00 25.629±12.34
ENST00000439080 N/A 28.889±5.76 N/A 29.351±0.00 27.580±11.39
ENST00000610369 46.533±0.00 N/A N/A N/A N/A
ENST00000613864 N/A 17.242±6.05 N/A N/A 44.394±21.21
ENST00000617757 152.097±0.00 N/A 247.466±0.00 N/A N/A
ENST00000621573 N/A 24.078±6.89 N/A 52.992±0.00 48.458±3.37

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00082Y CIL_00082Y_0001 VISTA
CIL_0008S2 CIL_0008S2_0001 VISTA
CIL_0008RU CIL_0008RU_0001 VISTA
CIL_0008JG CIL_0008JG_0001 VISTA
CIL_0008JY CIL_0008JY_0001 VISTA
CIL_00019T CIL_00019T_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001205 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003676 IEA nucleic acid binding
GO:0003690 IDA double-stranded DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0003723 IDA RNA binding
GO:0003730 IDA mRNA 3'-UTR binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005726 IEA perichromatin fibrils
GO:0005737 IEA cytoplasm
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006397 IEA mRNA processing
GO:0008219 IEA cell death
GO:0008380 IDA RNA splicing
GO:0016607 IEA nuclear speck
GO:0032024 IEA positive regulation of insulin secretion
GO:0034976 IEA response to endoplasmic reticulum stress
GO:0035061 IEA interchromatin granule
GO:0042802 IPI identical protein binding
GO:0043922 IDA negative regulation by host of viral transcription
GO:0044822 IDA poly(A) RNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0070935 IDA 3'-UTR-mediated mRNA stabilization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004452 tardbpl protein_coding Danio_rerio
ENSDARG00000040031 tardbp protein_coding Danio_rerio
ENSMUSG00000041459 Tardbp protein_coding Mus_musculus

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