ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: lysine (K)-specific demethylase 5C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000126012 KDM5C 9606 - X:53191321-53225422 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000349663 KDM5C-011 53221705-53225198 nonsense_mediated_decay
  ENST00000375379 KDM5C-006 53192929-53225422 protein_coding
  ENST00000375383 KDM5C-007 53192929-53225422 protein_coding
  ENST00000375401 KDM5C-005 53192152-53225422 protein_coding
  ENST00000404049 KDM5C-009 53192257-53225176 protein_coding
  ENST00000428012 KDM5C-013 53218315-53225194 nonsense_mediated_decay
  ENST00000429877 KDM5C-012 53217810-53225208 nonsense_mediated_decay
  ENST00000452825 KDM5C-201 53191321-53225422 protein_coding
  ENST00000465402 KDM5C-004 53201279-53210547 processed_transcript
  ENST00000467093 KDM5C-003 53217853-53221818 processed_transcript
  ENST00000477109 KDM5C-001 53197657-53198566 processed_transcript
  ENST00000481369 KDM5C-010 53201304-53202773 retained_intron
  ENST00000495519 KDM5C-002 53217829-53218737 processed_transcript
  ENST00000497100 KDM5C-008 53198490-53211658 retained_intron
  ENST00000497995 KDM5C-014 53215714-53217149 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000375379ENST00000375383ENST00000375401ENST00000404049ENST00000452825ENST00000497100
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000375379 N/A 7.637±0.94 2.427±0.00 9.714±5.18
ENST00000375383 N/A 4.077±0.61 N/A 4.738±0.00
ENST00000375401 0.602±0.00 7.297±2.86 4.171±0.00 7.430±3.25
ENST00000404049 2.591±1.17 11.793±3.39 3.580±0.00 6.814±3.29
ENST00000452825 N/A N/A N/A 2.124±1.56
ENST00000497100 N/A N/A N/A 12.264±7.93

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0032453 IDA histone demethylase activity (H3-K4 specific)
GO:0034720 IDA histone H3-K4 demethylation
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006124 kdm5c protein_coding Danio_rerio
ENSMUSG00000025332 Kdm5c protein_coding Mus_musculus

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