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ANGIOGENES

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000128050 PAICS 9606 + 4:56435741-56461368 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264221 PAICS-201 56435749-56461368 protein_coding
  ENST00000399688 PAICS-003 56436138-56461361 protein_coding
  ENST00000504188 PAICS-009 56436039-56441863 retained_intron
  ENST00000505164 PAICS-001 56435752-56459499 protein_coding
  ENST00000508554 PAICS-010 56448699-56451191 retained_intron
  ENST00000510584 PAICS-008 56436138-56442028 retained_intron
  ENST00000512576 PAICS-006 56436152-56459664 protein_coding
  ENST00000514888 PAICS-002 56435741-56461361 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000264221ENST00000399688ENST00000510584ENST00000512576ENST00000514888
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000264221 N/A 19.987±6.87 N/A 29.222±0.00 22.468±15.30
ENST00000399688 11.367±0.00 13.317±5.52 N/A N/A 8.888±5.76
ENST00000510584 N/A N/A N/A N/A 67.551±10.10
ENST00000512576 15.089±7.69 12.910±6.25 2.178±0.00 19.076±0.00 15.879±10.16
ENST00000514888 N/A N/A N/A N/A 6.725±2.74

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001WN CIL_0001WN_0001 CGP
CIL_0008G9 CIL_0008G9_0001 VISTA
CIL_0001WO CIL_0001WO_0001 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004638 TAS phosphoribosylaminoimidazole carboxylase activity
GO:0004639 IEA:TAS phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006144 TAS purine nucleobase metabolic process
GO:0006189 IEA 'de novo' IMP biosynthetic process
GO:0009113 TAS purine nucleobase biosynthetic process
GO:0009168 TAS purine ribonucleoside monophosphate biosynthetic process
GO:0016020 IDA membrane
GO:0042802 IPI identical protein binding
GO:0044281 TAS small molecule metabolic process
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033539 paics protein_coding Danio_rerio
ENSMUSG00000029247 Paics protein_coding Mus_musculus

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