ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: dedicator of cytokinesis 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130158 DOCK6 9606 - 19:11199295-11262481 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000294618 DOCK6-001 11199295-11262452 protein_coding
  ENST00000585609 DOCK6-003 11247258-11262481 retained_intron
  ENST00000585904 DOCK6-012 11229001-11235754 protein_coding
  ENST00000586482 DOCK6-011 11252404-11253667 retained_intron
  ENST00000586702 DOCK6-009 11199295-11203313 processed_transcript
  ENST00000587572 DOCK6-010 11252882-11254048 retained_intron
  ENST00000587656 DOCK6-006 11199497-11236497 protein_coding
  ENST00000587734 DOCK6-018 11199303-11201963 protein_coding
  ENST00000588429 DOCK6-016 11215611-11217296 retained_intron
  ENST00000588666 DOCK6-017 11202082-11208944 protein_coding
  ENST00000590452 DOCK6-013 11228840-11229332 retained_intron
  ENST00000590680 DOCK6-005 11227337-11238290 protein_coding
  ENST00000591750 DOCK6-004 11235899-11238921 retained_intron
  ENST00000592403 DOCK6-015 11216676-11217268 retained_intron
  ENST00000592463 DOCK6-007 11206181-11208758 processed_transcript
  ENST00000592550 DOCK6-014 11221986-11222324 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000294618ENST00000585609ENST00000586702ENST00000587656ENST00000587734
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000294618 7.968±2.70 14.235±4.84 10.743±0.00 20.921±0.00 21.859±14.67
ENST00000585609 N/A N/A N/A N/A 1.463±0.00
ENST00000586702 51.225±0.00 N/A 163.289±0.00 N/A N/A
ENST00000587656 17.011±0.00 13.067±4.11 40.131±0.00 17.879±0.00 16.146±11.17
ENST00000587734 325.842±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001EZ CIL_0001EZ_0002 CGP
CIL_0003Q6 CIL_0003Q6_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005829 TAS cytosol
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007596 TAS blood coagulation
GO:0043547 IEA positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035706 dock6 protein_coding Danio_rerio
ENSMUSG00000032198 Dock6 protein_coding Mus_musculus

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