ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: actinin, alpha 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130402 ACTN4 9606 + 19:38647649-38731583 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000252699 ACTN4-001 38647670-38731583 protein_coding
  ENST00000390009 ACTN4-010 38647738-38729447 protein_coding
  ENST00000424234 ACTN4-201 38647746-38729432 protein_coding
  ENST00000440400 ACTN4-004 38724157-38731583 protein_coding
  ENST00000477174 ACTN4-006 38728145-38729421 processed_transcript
  ENST00000489451 ACTN4-003 38710833-38717117 processed_transcript
  ENST00000495553 ACTN4-002 38648193-38709423 processed_transcript
  ENST00000497637 ACTN4-005 38727856-38729820 processed_transcript
  ENST00000586538 ACTN4-012 38708142-38717316 protein_coding
  ENST00000588618 ACTN4-007 38647649-38721878 retained_intron
  ENST00000589528 ACTN4-013 38647738-38730144 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000252699ENST00000390009ENST00000424234ENST00000440400ENST00000495553ENST00000497637ENST00000588618
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000252699 31.546±3.35 45.222±9.63 N/A 46.202±0.00 39.086±35.31
ENST00000390009 N/A 110.669±38.38 N/A 91.869±0.00 43.866±33.46
ENST00000424234 N/A N/A N/A N/A 40.156±14.79
ENST00000440400 41.296±0.00 N/A 26.427±0.00 N/A N/A
ENST00000495553 N/A 302.302±17.03 N/A N/A N/A
ENST00000497637 125.527±0.00 N/A N/A N/A 120.847±0.00
ENST00000588618 N/A 118.696±43.08 N/A 97.386±0.00 66.940±45.69

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0001725 IEA stress fiber
GO:0001882 IDA nucleoside binding
GO:0002576 TAS platelet degranulation
GO:0003779 TAS actin binding
GO:0005178 TAS integrin binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005911 IEA cell-cell junction
GO:0005925 IDA focal adhesion
GO:0007596 TAS blood coagulation
GO:0015031 IEA protein transport
GO:0030018 IEA Z disc
GO:0030168 TAS platelet activation
GO:0030529 IDA ribonucleoprotein complex
GO:0030863 IEA cortical cytoskeleton
GO:0031093 TAS platelet alpha granule lumen
GO:0031143 TAS pseudopodium
GO:0032403 IEA protein complex binding
GO:0032417 NAS positive regulation of sodium:proton antiporter activity
GO:0042803 TAS protein homodimerization activity
GO:0042981 NAS regulation of apoptotic process
GO:0043005 IEA neuron projection
GO:0043234 IDA protein complex
GO:0044822 IDA poly(A) RNA binding
GO:0047485 IEA protein N-terminus binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048549 IEA positive regulation of pinocytosis
GO:0051015 IDA actin filament binding
GO:0051017 IEA actin filament bundle assembly
GO:0051271 IEA negative regulation of cellular component movement
GO:0051272 IMP positive regulation of cellular component movement
GO:0051764 IEA actin crosslink formation
GO:0070062 IDA extracellular vesicular exosome
GO:0070830 IEA tight junction assembly
GO:1902396 IEA protein localization to tight junction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000054808 Actn4 protein_coding Mus_musculus

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