ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: solute carrier family 6 (neurotransmitter transporter), member 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130821 SLC6A8 9606 + X:153688099-153696593 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000253122 SLC6A8-002 153688099-153696593 protein_coding
  ENST00000413787 SLC6A8-008 153693054-153694576 protein_coding
  ENST00000429147 SLC6A8-006 153691461-153692215 protein_coding
  ENST00000430077 SLC6A8-005 153689467-153695327 protein_coding
  ENST00000442457 SLC6A8-009 153693267-153694420 protein_coding
  ENST00000457723 SLC6A8-001 153693462-153694164 protein_coding
  ENST00000466243 SLC6A8-010 153691118-153692082 processed_transcript
  ENST00000467402 SLC6A8-007 153691363-153693972 processed_transcript
  ENST00000476466 SLC6A8-004 153688723-153690881 processed_transcript
  ENST00000485324 SLC6A8-003 153692231-153695400 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000253122ENST00000430077ENST00000485324
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000253122 3.767±0.06 14.423±9.30 6.393±0.00 5.917±0.00 5.646±3.32
ENST00000430077 N/A 11.664±9.27 N/A 4.882±0.00 9.778±6.76
ENST00000485324 N/A N/A N/A N/A 0.560±0.60

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001UZ CIL_0001UZ_0001 CGP
CIL_0001UY CIL_0001UY_0001 CGP
CIL_0001UX CIL_0001UX_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005308 NAS creatine transmembrane transporter activity
GO:0005309 IEA creatine:sodium symporter activity
GO:0005328 IEA neurotransmitter:sodium symporter activity
GO:0005575 ND cellular_component
GO:0005886 TAS plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006600 TAS creatine metabolic process
GO:0006810 TAS transport
GO:0006814 IEA sodium ion transport
GO:0006836 IEA neurotransmitter transport
GO:0006936 TAS muscle contraction
GO:0008150 ND biological_process
GO:0015881 NAS creatine transport
GO:0016021 TAS:IEA integral component of membrane
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0055085 IEA transmembrane transport
GO:1902598 IEA creatine transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043646 slc6a8 protein_coding Danio_rerio
ENSMUSG00000019558 Slc6a8 protein_coding Mus_musculus

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