ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: phosphodiesterase 6A, cGMP-specific, rod, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132915 PDE6A 9606 - 5:149857955-149944793 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000255266 PDE6A-001 149857956-149944793 protein_coding
  ENST00000508173 PDE6A-002 149857956-149944793 retained_intron
  ENST00000512670 PDE6A-003 149860654-149867892 retained_intron
  ENST00000613228 PDE6A-201 149857957-149944793 protein_coding
  ENST00000617647 PDE6A-202 149857955-149944793 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000255266ENST00000512670ENST00000613228ENST00000617647
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000255266 N/A N/A N/A N/A 0.020±0.00
ENST00000512670 N/A 0.049±0.00 N/A N/A 0.013±0.00
ENST00000613228 0.054±0.00 0.045±0.03 0.124±0.00 N/A 0.038±0.05
ENST00000617647 N/A 0.108±0.03 N/A 0.120±0.00 0.012±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001JR CIL_0001JR_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004114 IEA 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0007165 IEA signal transduction
GO:0007601 IEA visual perception
GO:0007603 TAS phototransduction, visible light
GO:0016056 TAS rhodopsin mediated signaling pathway
GO:0022400 TAS regulation of rhodopsin mediated signaling pathway
GO:0046037 IMP GMP metabolic process
GO:0046872 IEA metal ion binding
GO:0047555 IMP 3',5'-cyclic-GMP phosphodiesterase activity
GO:0051480 IMP cytosolic calcium ion homeostasis
GO:0060041 IEA retina development in camera-type eye
GO:0097381 TAS photoreceptor disc membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000380 pde6a protein_coding Danio_rerio
ENSMUSG00000024575 Pde6a protein_coding Mus_musculus

Loading