ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: dual serine/threonine and tyrosine protein kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000133059 DSTYK 9606 - 1:205142505-205211566 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367161 DSTYK-002 205142505-205211566 protein_coding
  ENST00000367162 DSTYK-001 205142505-205211566 protein_coding
  ENST00000615388 DSTYK-201 205160006-205173393 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000367161ENST00000367162
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000367161 0.581±0.18 1.405±0.00 0.579±0.38
ENST00000367162 1.979±0.55 1.909±0.00 2.334±1.41

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004712 IEA protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0006468 IEA protein phosphorylation
GO:0016323 IDA basolateral plasma membrane
GO:0016324 IDA apical plasma membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0033674 IMP positive regulation of kinase activity
GO:0044344 IDA cellular response to fibroblast growth factor stimulus
GO:0045743 IMP positive regulation of fibroblast growth factor receptor signaling pathway
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000853 dstyk protein_coding Danio_rerio
ENSMUSG00000042046 Dstyk protein_coding Mus_musculus

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